Sökning: "Adipose tissue"
Visar resultat 31 - 35 av 421 avhandlingar innehållade orden Adipose tissue.
31. GH, IGF-1 and insulin in the regulation of lipid and lipoprotein metabolism
Sammanfattning : It is well known that growth hormone (GH) has profound effects on lipid and lipoprotein metabolism. Insulin-like growth factor-I (IGF-I) is believed to mediate some of the effects of GH via endocrine and paracrine mechanisms. Moreover, both GH and IGF-I are known to influence insulin secretion. LÄS MER
32. Pharmacological and genetic manipulation of adipose cell differentiation and metabolism
Sammanfattning : Adipose tissue dysfunction has a pivotal role in the development of obesity and related metabolic complications, such as insulin resistance, cardiovascular disease, and diabetes. The overall aim was to study the consequences of adipose exposure to pharmacological agents, as well as dysregulations in the expression of genes, potentially involved in adipose tissue dysfunction and related metabolic impairments. LÄS MER
33. Role of nuclear receptors in the regulation of human adipose tissue metabolism
Sammanfattning : Nuclear receptors modulate expression of genes involved in adipose tissue (AT) metabolism. Their improved understanding may provide new treatment options for metabolic disorders such as obesity, insulin resistance (IR) and type 2 diabetes (T2D). LÄS MER
34. Adverse drug effects on glucose and lipid metabolism: is human adipose tissue of importance?
Sammanfattning : Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic effects, such as hyperglycaemia, insulin resistance, and diabetes. Among such drugs are antipsychotics, prescribed for treatment of schizophrenia; statins, which inhibit cholesterol synthesis and prevent cardiovascular events; finally, potent anti-inflammatory agents, glucocorticoids. LÄS MER
35. Angiogenic mechanims in adipose tissue and tumor
Sammanfattning : Angiogenesis is involved in the development and progression of many human diseases, including cancer, cardiovascular diseases, chronic inflammation, and metabolic diseases. Despite differences in microenvironment under various pathological settings, angiogenic blood vessels share some common features in numerous diseases. LÄS MER