Sökning: "Adipose tissue"

Visar resultat 11 - 15 av 418 avhandlingar innehållade orden Adipose tissue.

  1. 11. Brown is the new white: consequences of white adipose tissue alterations in Huntington's disease

    Författare :Andy Mccourt; Biomarkörer vid hjärnsjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington’s disease; weight loss; white adipose tissue; brown adipose tissue; peripheral symptoms; R6 2 mice; UCP1; CREB1; gene expression;

    Sammanfattning : Huntington's disease (HD) is a devastating, inherited neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Peripheral symptoms, such as skeletal muscle wasting, progressive weight loss, altered body composition and endocrine disturbances exist alongside neurodegeneration. LÄS MER

  3. 12. Adipose Tissue Heterogeneity - Development and Application of Nonlinear Microscopy Methods

    Författare :Alexandra Paul; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; least squares decomposition; stem cells; multivariate spectral analysis; obesity; adipose tissue; adipogenesis; broadband coherent anti-Stokes Raman scattering; extracellular matrix;

    Sammanfattning : Although the negative health impacts of obesity have been well documented, the number of overweight or obese patients has and is predicted to continue rising. One of the causal factors of obesity is a constant positive energy balance mainly from excessively high caloric intake from food compared with limited physical activity (caloric expenditure). LÄS MER

  4. 13. Biodegradable magnesium implants, immunomodulation, and tissue repair/regeneration

    Författare :Heithem Ben Amara; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipose tissue; Biodegradable implants; Bone–implant interface; Bone marrow; Inflammation; Cellular mechanotransduction; Gene expression; Immunohistochemistry; Magnesium; Neovascularization; Osseointegration; Soft tissue injuries;

    Sammanfattning : The century-old paradigm of holding fractures with a metallic implant to enable bone repair, known as osteosynthesis, is still used today without alteration. Patients are increasingly being treated with metallic implants made of magnesium (Mg) that secure osteosynthesis and are reabsorbed in situ without the surgical re-entry that requires their permanent analogs. LÄS MER

  5. 14. Microarray analysis of gene expression in human adipocytes and adipose tissue

    Författare :Margareta Jernås; Göteborgs universitet; []
    Nyckelord :obesity; adipose tissue; insulin resistance; serum amyloid A; NAD P H:quinone oxidoreductase 1; Zinc-alpha2 glycoprotein; cell death-inducing DFFA-like effector A; DNA microarray;

    Sammanfattning : Obesity has reached epidemic proportions worldwide and is associated with several serious conditions such as insulin resistance, type 2 diabetes, hyperlipidemia and atherosclerosis. Adipose tissue exerts important endocrine and immune functions through the release of adipokines. LÄS MER

  7. 15. Role of caveolin-1 in brown adipose tissue

    Författare :Charlotte L. Mattsson; Barbara Cannon; Paul Pilch; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; caveolin; brown adipose tissue; metabolism; signaling; Physiology; Fysiologi; fysiologi; Physiology;

    Sammanfattning : Caveolae are 50-100 nm invaginations in the plasma membrane. Caveolae and the protein caveolin-1 (Cav1) have been shown to be important in many signaling pathways in different cell types; however, in some cell types caveolae and Cav1 do not seem to affect the investigated signaling pathways. LÄS MER