Sökning: "membrane orientation"
Visar resultat 21 - 25 av 55 avhandlingar innehållade orden membrane orientation.
21. Exploring the Molecular Dynamics of Proteins and Viruses
Sammanfattning : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. LÄS MER
22. Cell-protein-material Interactions on Bioceramics and Model Surfaces
Sammanfattning : The objective of this thesis was to investigate and characterize the interaction between blood proteins and different surfaces with emphasis on protein adsorption to bioceramics and model surfaces. Special effort was made to monitor the spontaneous and selective adsorption of proteins from human plasma and to examine the orientation, conformation and functional behavior of single proteins after adsorption. LÄS MER
23. Exploring Unorthodox Aquaporins : Characterization of NbXIPs & AtNIPs
Sammanfattning : AbstractAquaporins are membrane integral proteins that facilitate the transport of waterand/or other small neutral molecules across biological membranes in cells in allforms of life. Among the subfamilies of aquaporins in higher plants, the X IntrinsicProteins (XIPs) are the most recently discovered subfamily and the leastcharacterized. LÄS MER
24. Design and synthesis of glycose-derivatives and related molecules for cell membrane mimetics
Sammanfattning : A series of glucopyranose (α-D-glucose, β-D-glucose, D-gluconic acid and 6-amino-6-deoxy-D-glocuse) terminated alkanethiol acetals have been successfully synthesized. α and β-D-glucose were configured in controlled ways coupling with alkanethiol, in which bromosugar and trichloroacetirnidates were selected as activated glycosyl donors using different promoters tetraalkylammonium bromide (Et4NBr) and trimethylsilanetriflate (TMSOTf) respectively. LÄS MER
25. Colon cancer specific cytochrome P450 2W1 : polymorphism, membrane topology and endogenous roles in development
Sammanfattning : Cytochrome P450 2W1 (CYP2W1) belongs to a family of drug metabolizing monooxygenases with an unidentified yet endogenous function. CYP2W1 expression pattern has characteristic features of oncofetal genes. Previous studies have shown significant levels of CYP2W1 protein in 30% of human colon cancers and in 50% of corresponding liver metastases. LÄS MER