Sökning: "Ola Carlsson"
Visar resultat 1 - 5 av 28 avhandlingar innehållade orden Ola Carlsson.
1. Implantation-Site Dependent Differences in Engraftment and Function of Transplanted Pancreatic Islets
Sammanfattning : Transplanting pancreatic islets into the liver through the portal vein is currently the most common procedure in clinical islet transplantations for treating patients with brittle type 1 diabetes. However, most islet grafts fail within a 5-year period necessitating retransplantation. LÄS MER
2. Peripheral immunity in patients with autoimmune endocrine diseases and the influence of physiological adaptions during pregnancy
Sammanfattning : Type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), Graves’ disease (GD), and autoimmune Addison’s disease (AD) appear to share immunogenetic mechanisms. This idea is not novel, as “autoimmune tautology” is an established concept. LÄS MER
3. Capillary and interstitial transport of fluid and solutes across the peritoneal membrane
Sammanfattning : According to the three-pore model of peritoneal transport the major exchange pathway between the blood and the peritoneal cavity is represented by “small pores”, permeable to small solutes and water. Osmotically induced fluid flow, as during peritoneal dialysis (PD), is postulated to occur to a great extent through a water-only pathway, whereas proteins are predicted to reach the peritoneal cavity by unidirectional convection across “large pores”. LÄS MER
4. Microcirculation in native and transplanted rodent pancreatic islets with special reference to the influence of diabetes mellitus
Sammanfattning : The aim of the present work was to characterize the islet microcirculation in animal models of type 1 and type 2 diabetes, as well as in islets transplanted to diabetic or normoglycemic recipients. For this purpose, a microsphere technique was evaluated and applied for measurements of islet blood flow in mice. LÄS MER
5. Epidemiological aspects of drug-related vitamin D deficiency and osteoporotic fractures
Sammanfattning : Background: Vitamin D deficiency, secondary osteoporosis and low-energy fractures (LEF) as side effects of specific drugs were first described more than half a century ago. These effects are recognized in guidelines where patients prescribed risk drugs are recommended follow-up with testing and supplementation. LÄS MER