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Visar resultat 11 - 15 av 128 avhandlingar som matchar ovanstående sökkriterier.

  1. 11. The Role of Shb in Angiogenesis, FGF and VEGF Signalling in Endothelial Cells

    Författare :Kristina Holmqvist; Michael Welsh; Eva Degerman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Shb; Src; FAK; Angiogenesis; VEGFR-2; FGFR-1; Endothelial cells; Spreading; Stress fiber formation; siRNA; VEGF; FGF; Differentiation; Migration; Tube formation; RNAi; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Angiogenesis is defined as the formation of new capillary blood vessels from pre-existing ones. This process involves several steps including: migration, proliferation and differentiation of endothelial cells into blood vessels. LÄS MER

  3. 12. VEGFR-2 in Endothelial Differentiation and Vascular Organization

    Författare :Dan Edholm; Lena Claesson-Welsh; Xiujuan Li; Victoria Bautch; Uppsala universitet; []
    Nyckelord :Molecular medicine; Embryonic stem; VEGFR-2; Flk1; KDR; VEGF; vasculogenesis; angiogenesis; embryoid body; Molekylärmedicin;

    Sammanfattning : The cardiovascular system is the first functional organ to develop during embryogenesis. As the embryo reaches above a certain size, passive diffusion of gases and nutrients is no longer compatible with efficient growth. LÄS MER

  4. 13. Functional genomics of vascular endothelial cells

    Författare :Elisabet Wallgard; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Vasculature; endothelial cells; angiogenesis; vascular endothelial growth factor VEGF ; Notch; transcriptome; genomics; microarray; tumor; retina; morpholino knockdown;

    Sammanfattning : Angiogenesis, the formation of new blood vessels from preexisting ones, is a process involved in normal development as well as in several pathological conditions, such as cancer, ischemic heart disease, wound healing and certain retinal complications. Antiangiogenic targeting is therefore a promising new therapeutic principle. LÄS MER

  5. 14. On vascular endothelial growth factor B and platelet-derived growth factor C : two members of the VEGF/PDGF family of growth factors

    Författare :Karin Aase; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Vascular endothelial growth factors (VEGFs), platelet-derived growth factors (PDGFs) and their receptors are important for normal development. They have also been implicated in many pathological conditions. VEGFs have been shown to play an important role in the development of both blood and lymphatic vessels. LÄS MER

  7. 15. Human Endometrial Angiogenesis : An Immunohistochemical Study of the Endometrial Expression of Angiogenic Growth Factors and Their Corresponding Receptors

    Författare :Björn Möller; Matts Olovsson; Bo Lindblom; Kristina Gemzell-Danielsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Human endometrium; angiogenesis; menstrual cycle; endothelial cells; immunohistochemistry; western blot; VEGF; VEGFR; FGF-2; FGFR; EGF; EGFR; levonorgestrel-releasing intrauterine system; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : The human endometrium undergoes dramatic changes in morphology and function during the menstrual cycle. Recurrent angiogenesis (the formation of new blood vessels) is of utmost importance for oxygen supply and nourishment of the rapidly growing endometrial tissue. LÄS MER