Sökning: "trigeminal system"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden trigeminal system.

  1. 1. Distribution of CGRP and CGRP receptor in the trigeminovascular system and CNS

    Författare :Sajedeh Eftekhari; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CGRP; CLR; RAMP1; migraine; trigeminovascular system; pain; cerebellum;

    Sammanfattning : Calcitonin gene-related peptide (CGRP) has a key role in the pathophysiology of migraine and is associated with activation of the trigeminovascular system. Recently, CGRP receptor antagonists have been developed with clinical efficacy. LÄS MER

  3. 2. Messenger molecules and receptors in the human trigeminovascular system

    Författare :Mingyan Hou; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; neurofysiologi; Neurology; neuropsychology; neurophysiology;

    Sammanfattning : The initiation of a migraine attack involves a primary central nervous system dysfunction with subsequent activation of the trigeminovascular system. In trigeminal ganglia, the expression of calcitonin gene-related peptide (CGRP), substance P (SP) and nitric oxide synthase (NOS) have been demonstrated by immunocytochemistry. LÄS MER

  4. 3. Development requirements of neurotrophins in the mammalian nervous system

    Författare :Wael M Elshamy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The survival of the mammalian peripheral nervous system neurons has long been known to depend on neurotrophic factor support during the period of programmed cell death. In fact this was the original hypothesis, put forward after the discovery of the prototype, nerve growth factor (NGF). LÄS MER

  5. 4. Central projections of sensory innervation of cranial vessels

    Författare :Yi Liu; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; Spinothalamic; Neurology; neuropsychology; neurophysiology; Neural tracing; trigeminal nerve; Headache; Cranial vessel; Brainstem; neuropsykologi; neurofysiologi;

    Sammanfattning : Primary headaches (e.g. migraine and cluster headache), the symptoms of which is associated with cranial vascular activity, is likely to be dependent on a primary central nervous system dysfunction. LÄS MER

  7. 5. Physiological roles of amyloid precursor protein in vivo - zebrafish as a model

    Författare :Jasmine Chebli; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloid-beta precursor protein; amyloid precursor protein-b; zebrafish; physiological functions; development; trigeminal ganglia; ependyma; cilia; proteomics; translational adaptation;

    Sammanfattning : Amyloid-beta precursor protein (APP) is an evolutionarily conserved transmembrane protein expressed in many different tissues. APP belongs to a gene family consisting of two other APP-like proteins (APLP1 and APLP2). LÄS MER