Sökning: "RAMP1"

Hittade 3 avhandlingar innehållade ordet RAMP1.

  1. 1. Distribution of CGRP and CGRP receptor in the trigeminovascular system and CNS

    Författare :Sajedeh Eftekhari; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CGRP; CLR; RAMP1; migraine; trigeminovascular system; pain; cerebellum;

    Sammanfattning : Calcitonin gene-related peptide (CGRP) has a key role in the pathophysiology of migraine and is associated with activation of the trigeminovascular system. Recently, CGRP receptor antagonists have been developed with clinical efficacy. LÄS MER

  3. 2. The calcitonin gene family of peptides : receptor expression and effects on bone cells

    Författare :Susanne Granholm; Ulf Lerner; Pernilla Lundberg; Göran Andersson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; CT family of peptides; osteoclast differentiation; bone resorption; CTR; CRLR; RAMPs; Cell biology; Cellbiologi;

    Sammanfattning : The calcitonin gene family of peptides consists of calcitonin (CT), two calcitonin gene related peptides (α-CGRP, β-CGRP), adrenomedullin (ADM), amylin (AMY), three calcitonin receptor activating peptides (CRSP1-3) and intermedin/adrenomedullin2 (IMD). These peptides bind to one of two G protein -coupled receptors, the calcitonin receptor (CTR) or the calcitonin receptor-like receptor (CRLR). LÄS MER

  4. 3. Deciphering the role of genetics and circadian rhythm in cluster headache

    Författare :Carmen Fourier; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cluster headache (CH) is a complex neurovascular disorder with a distinct circadian attack pattern. Although many aspects of the disease’s pathophysiology remain to be elucidated, it is likely caused by a combination of different genetic and environmental risk factors. LÄS MER