Sökning: "the infantile"

Visar resultat 11 - 15 av 29 avhandlingar innehållade orden the infantile.

  1. 11. Unraveling the role of NOTCH3 dysfunction in disease and for therapy development : a focus on CADASIL

    Författare :Daniel V Oliveira; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The Notch signaling pathway, including the Notch3 receptor, is involved in many pivotal contexts of cell signaling and cell fate determination processes during development and in adulthood. Different mutations in the NOTCH3 receptor, which is highly expressed in vascular smooth muscle cells (VSMC), are associated with various diseases, including developmental disorders, several forms of cancer, and vascular dementia. LÄS MER

  3. 12. Structure and host-receptor recognition studies of Gram-negative bacterial fimbriae assembled via the chaperone/Usher Pathway

    Författare :Saumendra Prasad Roy; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Enterotoxigenic E. coli (ETEC), enteroaggregative E. coli (EAEC), and Yersinia enterocolitica (YE) are the principle etiological agents of acute and persistent diarrhea worldwide including resource-poor and industrialized regions. LÄS MER

  4. 13. Genetic studies of children with mental retardation

    Författare :Saideh Rajaei; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mental retardation; Rett syndrome; RTT; early onset infantile RTT; MECP2; SMR; SNP array; copy number variations; CNV; MECP2 duplication syndrom;

    Sammanfattning : Mental retardation (MR) is characterised by significant limitations in intellectual function and adaptive behaviour. It is estimated that MR affects up to 3% of the population in Europe. Patients with MR are an aetiologically heterogeneous group. Approximately 25-35% of the patients have a genetic diagnosis. LÄS MER

  5. 14. Candida infections in immunocompromised children

    Författare :Lena Klingspor; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Anti-Candida antibodies; bone marrow transplantation; Candida antigen; Candida immunology; candidosis diagnosis; children; infantile diarrhoea; leukaemia; liver transplantation; risk factors.;

    Sammanfattning : Objective: Deep Candida infection (DCI) is a serious complication with high mortality in immunocompromised patients. The following studies (I, II, III, IV and V) were designed to investigate the relationship between infantile diarrhoea and faecal occurrence of Candida spp. LÄS MER

  7. 15. Hydrocephalus in children. Epidemiology and outcome

    Författare :Eva-Karin Persson; Göteborgs universitet; []
    Nyckelord :Prevalence; Epidemiology; Hydrocephalus; MMC; Treatment; Outcome;

    Sammanfattning : Aims: To analyse trends in the live-birth prevalence of infantile hydrocephalus and hydrocephalus associated with myelomeningocele (MMC) during the period 1989-2002 and to study the outcome in terms of learning disability, cerebral palsy, epilepsy and visual deficits. Another objective was to explore motor function and disability profiles in various aetiological and gestational-age subgroups and to see whether treatment complications and neuroradiological findings correlate with outcome. LÄS MER