Sökning: "systemic risk"

Visar resultat 16 - 20 av 465 avhandlingar innehållade orden systemic risk.

1. 16. The genetics of systemic lupus erythematosus : Mapping of susceptibility loci for human SLE

   Författare :Anna-Karin B. Lindqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Systemic lupus erythematosus; complex diseases; genetic susceptibility; linkage analysis; genome scan; candidate gene; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

   Sammanfattning : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease affecting organs such as skin, jointsand kidneys. Characteristic for the disease is increased production of autoantibodies, in particular against dsDNA. Previous studies of SLE in mouse models and in humans indicate polygenic inheritance and genetic heterogeneity. LÄS MER

3. 17. Studies on cardiovascular risk factors in systemic lupus erythematosus

   Författare :Johanna Gustafsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Systemic Lupus Erythematosus (SLE) is an autoimmune, inflammatory disease that mainly affects women. The prognosis of SLE has improved dramatically, but mortality rates are still higher than in the general population. LÄS MER

4. 18. Systemic sclerosis. Novel molecular and epidemiological features of disease

   Författare :Kristofer Andréasson; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; fibrosis; COMP; calprotectin; biomarker; gastrointestinal;

   Sammanfattning : Systemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. LÄS MER

5. 19. Risk markers and incidence of atrial fibrillation in northern Sweden

   Författare :Cecilia Johansson; Lars Johansson; Jonas Andersson; Marcus Lind; Marie Eriksson; Mårten Rosenqvist; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial fibrillation; atrial flutter; incidence; provoking factors; types of atiral fibrillation; stroke risk; alcohol consumption; problem drinking; weight; height; weight change; normal blood pressure; high normal blood pressure; Förmaksflimmer; förmaksfladder; incidens; provocerande faktorer; typer av förmaksflimmer; strokerisk; alkoholkonsumtion; alkoholproblem; vikt; längd; viktförändring; normalt blodtryck; högt normalt blodtryck; medicin; Medicine;

   Sammanfattning : Background: Atrial fibrillation (AF) is the most common clinically significant arrythmia with a prevalence of approximately 3% in the general population. Less is known about the incidence of AF. In order to reduce the incidence of AF, it is of essence to identify modifiable risk factors for the disease. LÄS MER

7. 20. Biomarkers of inflammation in atrial fibrillation

   Författare :Julia Aulin; Jonas Oldgren; Ziad Hijazi; Lars Wallentin; Håkan Wallén; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atrial fibrillation; biomarkers; inflammation; inflammatory biomarkers; oral anticoagulation; heart failure; left ventricular function; ejection fraction; risk assessment; risk prediction; interleukin 6 IL-6 ; C-reactive protein CRP ;

   Sammanfattning : Atrial fibrillation (AF) is common and associated with increased risk of stroke, heart failure (HF) and mortality. Inflammation is linked to AF.The overall aim of this thesis was to investigate inflammatory activity and cardiovascular outcomes and mortality in patients with AF on effective oral anticoagulation. LÄS MER