Sökning: "single nucleotide polymorphisms"
Visar resultat 21 - 25 av 220 avhandlingar innehållade orden single nucleotide polymorphisms.
21. Biological Markers of Fertility
Sammanfattning : Infertility affects 15 % of couples, which corresponds to 60 - 80 million worldwide. The microenvironments in which the oocyte, embryo and fetus mature are vital to the establishment and development of a healthy pregnancy. LÄS MER
22. Genetic variation at the human tissue-type plasminogen activator locus
Sammanfattning : Tissue-type plasminogen activator (tPA) is the key initiator of intravascular fibrinolysis. Family studies suggest that tPA release is regulated by hereditary factors. LÄS MER
23. Parallel target selection by trinucleotide threading
Sammanfattning : DNA is the code for all life. Via intermediary RNA the information encoded by the genome is relayed to proteins executing the various functions in a cell. Together, this repertoire of inherently linked biological macromolecules determines all characteristics and features of a cell. LÄS MER
24. Interrogation of Nucleic Acids by Parallel Threading
Sammanfattning : Advancements in the field of biotechnology are expanding the scientific horizon and a promising era is envisioned with personalized medicine for improved health. The amount of genetic data is growing at an ever-escalating pace due to the availability of novel technologies that allow massively parallel sequencing and whole-genome genotyping, that are supported by the advancements in computer science and information technologies. LÄS MER
25. Antibody responses and Fc gamma receptor IIa polymorphism in relation to Plasmodium falciparum malaria
Sammanfattning : Immunity to asexual blood-stage of Plasmodium falciparum malaria is believed to be associated with protective antibodies of certain immunoglobulin classes and subclasses. This thesis addressed the importance of antibodies in relation to malaria infection and their effective interactions with Fc gamma receptor IIa (FcyRIIa) polymorphisms. LÄS MER