Sökning: "ovarian response"

Visar resultat 1 - 5 av 84 avhandlingar innehållade orden ovarian response.

1. 1. Ovarian cancer : Treatment results, prognostic factors, and tumor marker surveillance

   Författare :Thomas Högberg; Claes Tropé; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : The total population-based material of 426 ovarian malignancies in the Southeast Health Care Region of Sweden during 1984-1987 was surveyed. It seems that with a program of cytoreductive surgery followed by a cisplatinum chemotherapy combination in the metastasizing cases the overall survival figures have improved. LÄS MER

3. 2. Reproductive and Metabolic Consequences of the Polycystic Ovarian Syndrome

   Författare :Miriam Hudecova; Inger Sundström Poromaa; Jan Holte; Matts Olovsson; Per Olof Janson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; polycystic ovarian syndrome; long-term follow-up; ovarian reserve; anti-Müllerian hormone; insulin sensitivity; early insuline response; impaired glucose tolerance; diabetes; endothelial function; endothelial-dependent vasodilation; Obstetrics and gynaecology; Obstetrik och gynekologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Polycystic ovary syndrome (PCOS) is a complex clinical condition characterized by hyperandrogenism and chronic oligo/anovulation. Infrequent ovulation and metabolic alterations in women with PCOS are associated with subfertility and probably increased miscarriage rates compared with normal fertile women. LÄS MER

4. 3. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes

   Författare :Alireza Labani Motlagh; Lucia Mincheva-Nilsson; Ola Winqvist; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; EOC; HGSC; exosomes; NKG2D; MICA B; ULBP; DNAM-1; PVR; nectin-2; lncRNAs; immune suppression; anti-tumor immunity; NK-cell cytotoxicity; cytokines; Th1; Th2; T regulatory response; inflammation; tumor microenvironment;

   Sammanfattning : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. LÄS MER

5. 4. Ovarian Reserve and Assisted Reproduction

   Författare :Thomas Brodin; Jan Holte; Matts Olovsson; Lars Berglund; Juha Tapanainen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AFC; AMH; anti-Müllerian hormone; antral follicle count; follicle-stimulating hormone; FSH; ICSI; infertility; intracytoplasmic sperm injection; in vitro fertilization; IVF; LH; live birth; luteinizing hormone; menstrual cycle; menstrual cycle length; ovarian reserve; pregnancy; reproductive endocrinology; reproductive technology; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Treatment success in IVF-ICSI is mainly limited by female age, but differences in ovarian reserve (OR; the remaining pool of oocytes and their quality) between individuals modify treatment prerequisites among women of similar age. OR may be assessed by OR tests (ORTs). LÄS MER

7. 5. Hunting a Silent Killer. Biomolecular Approaches in Ovarian Cancer

   Författare :Nicolai Arildsen; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovarian cancer; Molecular biology; genetic variant; TP53 mutation; early detection; Drug Screening Assays; Antitumor; bioinformatics; next generation sequencing; NGS; prognostic and predictive biomarkers; ovarian clear cell cancer; high-grade serous ovarian cancer;

   Sammanfattning : Ovarian cancer is a heterogeneous disease and recent advances in improving patient outcome havebeen limited. It is estimated that a woman’s risk of developing ovarian cancer during her lifetime is about 1 in 70, making it a frequently occurring cancer type in women. LÄS MER