Sökning: "merozoites"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet merozoites.

  1. 1. Antibody responses and Fc gamma receptor IIa polymorphism in relation to Plasmodium falciparum malaria

    Författare :Nnaemeka C. Iriemenam; Klavs Berzins; Marita Troye-Blomberg; Philippe Deloron; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; malaria; Plasmodium falciparum; blood-stage; antibodies; antigens; logistic models; risk factors; age factors; merozoites; IgG subclasses; Fc gamma RIIa; single nucleotide polymorphism; ethnicity; endemicity; disease susceptibility; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Immunity to asexual blood-stage of Plasmodium falciparum malaria is believed to be associated with protective antibodies of certain immunoglobulin classes and subclasses. This thesis addressed the importance of antibodies in relation to malaria infection and their effective interactions with Fc gamma receptor IIa (FcyRIIa) polymorphisms. LÄS MER

  3. 2. Variable surface molecules of the plasmodium falciparum infected erythrocyte and merozoite

    Författare :Malin Haeggström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :P.falciparum; infected erythrocytes; transport; Maurer s clefts; antigenic variation; PfEMP1; RIFIN; SURFIN; merozoites; subgroups;

    Sammanfattning : As Plasmodium falciparum parasites matures within the infected erythrocyte (IE) it produces a number of various proteins, which are transported out to the cell surface where they are exposed to the host immune system. To avoid recognition and elimination by the liver and spleen these proteins can undergo antigenic variation, a phenomenon where the parasites switch from expressing one variant to' another, both belonging to the same gene-family. LÄS MER

  4. 3. Malaria and polypeptides of Plasmodium falciparum at the infected erythrocyte surface

    Författare :Mia Palmkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is one of the top three most lethal infectious diseases in the world after tuberculosis and HIV. The disease is caused by intracellular parasites of the genus Plasmodium spp. LÄS MER

  5. 4. Towards understanding the SURFIN protein family and var genes in Plasmodium falciparum

    Författare :Fingani Annie Mphande; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Plasmodium falciparum, the parasite responsible for severe malaria, has been shown to use different protein families for its survival and proliferation within the human host. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), a protein responsible for the cytoadherence of parasitized red blood cells (pRBCs) has been implicated in severe disease. LÄS MER

  7. 5. Regulation of Plasmodium falciparum virulence genes and immune response to surface antigens in placental malaria

    Författare :Kim Brolin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria infection caused by the parasite Plasmodium falciparum is a deadly torment, especially for young children and pregnant women residing in sub-Saharan Africa. Much of the parasites virulence is due to its ability to constantly vary the adhesive molecules expressed on the surface of infected red blood cells (iRBCs). LÄS MER