Sökning: "ribosomal binding site"

Visar resultat 11 - 15 av 35 avhandlingar innehållade orden ribosomal binding site.

  1. 11. Studies on the functional interaction of translation initiation factor IF1 with ribosomal RNA

    Författare :Jaroslav Belotserkovsky; Leif Isaksson; Diarmaid Hughes; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; ribosome; rRNA mutation; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Translation initiation factor IF1 is a small, essential and ubiquitous protein factor encoded by a single infA gene in bacteria. Although several important functions have been attributed to IF1, the precise reason for its indispensability is yet to be defined. LÄS MER

  3. 12. The ribosome, stringent factor and the bacterial stringent response

    Författare :Rose-Marie Jenvert; Lovisa Holmberg Schiavone; Suparna Sanyal; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribosome; stringent factor; stringent response; tRNA; ribosomal protein L11; pppGpp; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Sammanfattning : The stringent response plays a significant role in the survival of bacteria during different environmental conditions. It is activated by the binding of stringent factor (SF) to stalled ribosomes that have an unacylated tRNA in the ribosomal A-site which leads to the synthesis of (p)ppGpp. LÄS MER

  4. 13. Assembly and transport of messenger and ribosomal RNP particles in the dipteran Chironomus tentans

    Författare :Teresa Soop; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Gene expression in eukaryotic organisms commences with the synthesis of a precursor RNA, which has to be extensively processed to yield a mature RNA molecule. In addition to processing, the RNA molecule needs to associate with a proper set of proteins. LÄS MER

  5. 14. Determinants of peptidyl-tRNA drop-off from E. coli Ribosomes : Effects of antibiotics, mutations and translation factors

    Författare :Reza Karimi; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : During protein synthesis, some peptidyl-tRNA molecules dissociate from the ribosomes and become hydrolysed by peptidyl-tRNA hydrolase (Pth). Two different in vitro systems, poly(U) and natural mRNA programmed ribosomes, have been used in order to determine dissociation (drop-off) rates of deacylated- and peptidyl-tRNAs from different sites on ribosomes. LÄS MER

  7. 15. Dynamics in Protein Synthesis, Structural Studies of Translation Factors

    Författare :Martin Laurberg; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; Flexibility; Fusidic Acid; tRNA; Translation Factors; Ribosome; Molekylär biofysik;

    Sammanfattning : Protein biosynthesis is performed on ribosomes. The ribosome is a complex of ribosomal RNA and proteins forming two subunits. A messenger RNA strand is decoded on the small subunit by charged aminoacyl transfer RNA (aa-tRNA) molecules and each tRNA molecule delivers its amino acid to the growing polypeptide chain on the large subunit. LÄS MER