Sökning: "reductive evolution"

Visar resultat 6 - 10 av 11 avhandlingar innehållade orden reductive evolution.

  1. 6. Dynamics of the Bacterial Genome : Rates and Mechanisms of Mutation

    Författare :Sanna Koskiniemi; Dan Andersson; Diarmaid Hughes; Ivan Matic; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bacteria; bacterial evolution; genome reduction; gene loss; serial passage; DNA homology; tranlesion DNA polymerase; stress; Microbiology; Mikrobiologi; Bacteriology; Bakteriologi; Evolutionary Genetics; Evolutionär genetik; Mikrobiologi; Microbiology;

    Sammanfattning : Bacterial chromosomes are highly dynamic, continuously changing with respect to gene content and size via a number of processes, including deletions that result in gene loss. How deletions form and at what rates has been the focus of this thesis. In paper II we investigated how chromosomal location affects chromosomal deletion rates in S. LÄS MER

  3. 7. Plant type II NAD(P)H dehydrogenases : Structure, regulation and evolution of NDB proteins

    Författare :Mengshu Hao; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis; Ca2 ; Electron transport; NDH-2; NDB; pH; NADH; NADPH; Plant mitochondria; Potato; Type II NAD P H dehydrogenase;

    Sammanfattning : In living organisms, respiration is a biological process degrading different carbon substrates, consuming O2, and releasing the carbon as CO2. Plants have several alternative enzymes that are involved in the respiratory processes, as compared to animals. LÄS MER

  4. 8. Molecular evolutionary studies of genome degradation in bacteria

    Författare :Jan O. Andersson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The genus Rickettsia belongs to the α-proteobacteria and consists of obligate intracellular bacteria, which often are pathogenic for humans. All Rickettsia have small genomes, highly adapted to an intracellular lifestyle. LÄS MER

  5. 9. Structure Function Relationships in Pyrimidine Degrading and Biocatalytic Enzymes, and Their Implications for Cancer Therapy and Green Chemistry

    Författare :Dirk Maurer; Doreen Dobritzsch; Mikael Widersten; Rikkert Wierenga; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; β-Ureidopropionase; Dihydropyrimidine Dehydrogenase; Alcohol Dehydrogenase; Pyrimidine catabolism; 5-Fluorouracil; CASTing; X-ray Crystallography;

    Sammanfattning : This thesis includes the work of two separate projects, studies on pyrimidine degrading enzymes and studies on in vitro evolved enzymes. The common denominator of both projects was the use of structural information to explain functional effects, observed in the studied biocatalysts. LÄS MER

  7. 10. Industrial Systems Biology and Metabolic Engineering of Saccharomyces cerevisiae

    Författare :José Manuel Otero; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metabolic engineering; industrial systems biology; Saccharomyces cerevisiae;

    Sammanfattning : Saccharomyces cerevisiae is the most well characterized eukaryote, the preferred microbial cell factoryfor the largest industrial biotechnology product (bioethanol), and a robust commercially compatible scaffold to be exploited for diverse chemical production. Succinic acid is a highly sought after added-value chemical whichis not overproduced in native S. LÄS MER