Sökning: "protein folding"
Visar resultat 11 - 15 av 243 avhandlingar innehållade orden protein folding.
11. Protein Folding and DNA Origami
Sammanfattning : In this thesis, the folding process of the de novo designed polypeptide chignolin was elucidated through atomic-scale Molecular Dynamics (MD) computer simulations. In a series of long timescale and replica exchange MD simulations, chignolin’s folding and unfolding was observed numerous times and the native state was identified from the computed Gibbs free-energy landscape. LÄS MER
12. Protein Folding Studied by Site Directed Mutagenesis
Sammanfattning : The N-terminal RNA binding domain of U1A has been shown to fold in a two-state process without accumulating any intermediates. U1A has a symmetrically curved chevron plot which seems to result mainly from changes of the transition state. LÄS MER
13. Protein folding studies of human superoxide dismutase and ALS associated mutants
Sammanfattning : Proteins are among the most abundant biological macromolecules. The cellular machinery is coupled to exact structural shape and properties of the more than 100 000 different proteins. Still, proteins can sometimes completely change their character and as a result trigger neuro degenerative disease. LÄS MER
14. Studies on spinach plastocyanin and mutants : Expression in Escherichia coli, folding and function
Sammanfattning : Photosynthesis is a process in which photons from sunlight excite chlorophylls in the thylakoid membranes of plants, algae and cyanobacteria. The photo-oxidised reaction centre chlorophyll P700 is re-reduced by an electron transferred from the soluble, blue copper protein plastocyanin. LÄS MER
15. Modeling of Protein Folding and Genetic Networks
Sammanfattning : Models for potein folding are developed and applied to peptides and small proteins with both α-helix and β-sheet structure. The energy functions, in which effective hydrophobicity forces and hydrogen bonds are taken to be the two central terms, are sequence-based and deliberately kept simple. LÄS MER