Sökning: "protein encapsulation"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden protein encapsulation.

  1. 1. OSTE Microfluidic Technologies for Cell Encapsulation and Biomolecular Analysis

    Författare :Xiamo Zhou; Wouter van der Wijngaart; Ellis Meng; KTH; []
    Nyckelord :Microfluidics; microfabrication; cell encapsulation; core-shell particle; microparticle synthesis; off-stoichiometry-thiol-ene; OSTE; OSTE ; lab-on-a-chip; surface modification; core-shell particle co-synthesis; microar- ray; micromixer; bonding; surface modification; droplet microfluidics; protein screening.; Mikrofluidik; mikrofabrikation; cellinkapsling; cores-shell kap- sel; mikrokapselsyntes; lab-on-chip; ickestökiometrisk tiol-en; OSTE; OSTE ; ytmodifiering; samtidig syntes av core-shellkapslar; mikroarray; mikromixer; sammanfogning; dropletmikrofluidik; proteindetektion.; Tillämpad medicinsk teknik; Applied Medical Technology;

    Sammanfattning : In novel drug delivery system, the encapsulation of therapeutic cells in microparticles has great promises for the treatment of a range of health con- ditions. Therefore, the encapsulation material and technology are of great importance to the validity and efficiency of the advanced medical therapy. LÄS MER

  2. 2. Spray-Dried Powders for Inhalation : Particle Formation and Formulation Concepts

    Författare :Jessica Elversson; Göran Alderborn; Anna Millqvist-Fureby; Lars Hovgaard; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Spray drying; Particle formation; Density; Protein formulation; Encapsulation; Coating; Competitive adsorption; Polymer; ESCA; AFM; FTIR; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : Spray drying is a method with a high potential in the preparation of protein particles suitable for pulmonary delivery. However, surface induced denaturation of bio-molecules during atomization and subsequent drying can be substantial and it is therefore important to develop new formulation concept for concurrent encapsulation and stabilization of proteins during spray drying. LÄS MER

  3. 3. Phytoglobins: Elucidation of Structural, Functional and Practical Features of Non-Symbiotic Plant Hemoglobins

    Författare :Simon Christensen; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hemoglobin; Fytoglobin; Hexakoordination; Karaktärisering; Protein design; Rekombinant protein production; Kromatografi; kristallografi; Dimerisering; Protein Dynamik;

    Sammanfattning : Phytoglobins (Pgb) (plant hemoglobins) are heme-containing proteins and less well known in comparison to the mammalian counterparts hemoglobin (Hb) andmyoglobin (Mb). They share the same secondary structure as other globin-related proteins, six to eight α-helices comprising the myoglobin-fold (Mb-fold) with one prosthetic heme moiety per subunit. LÄS MER

  4. 4. The Design and Structure Prediction of Protein Oligomers

    Författare :Robert Lizatovic; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; virus capsids; coiled coils; molecular replacement; symmetry; Rosetta; protein design; structure prediction;

    Sammanfattning : The minimum free energy state of a protein (the native state) is encoded by its amino-acid sequence. Due to the many torsional degrees of freedom (DOF) available to a polypeptide chain, a vast number of conformations is possible. LÄS MER

  5. 5. Blood protein coated model biomaterials : preparation, and cell and tissue response

    Författare :Eva Jansson; Hans Elwing; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Solid biomaterials are widely used in bone and in soft tissue applications. Problems may then arise due to a prolonged inflammation in the proximity of the implant, resulting in the formation of a fibrous capsule and a low vascularisation near the interface. LÄS MER