Sökning: "Protein formulation"
Visar resultat 1 - 5 av 58 avhandlingar innehållade orden Protein formulation.
1. Spray-Dried Powders for Inhalation : Particle Formation and Formulation Concepts
Sammanfattning : Spray drying is a method with a high potential in the preparation of protein particles suitable for pulmonary delivery. However, surface induced denaturation of bio-molecules during atomization and subsequent drying can be substantial and it is therefore important to develop new formulation concept for concurrent encapsulation and stabilization of proteins during spray drying. LÄS MER
2. Membrane protein topogenesis
Sammanfattning : The membranes of cells are highly complex and heterogeneous structures that fulfill multiple vital tasks. They form thin barriers that seal out the environment, thus defining the cell’s boundaries. LÄS MER
3. Combinatorial protein engineering applied to enzyme catalysis and molecular recognition
Sammanfattning : The recent development of methods for constructing andhandling large collections (libraries) of proteins, from whichvariants with desired traits can be isolated, hasrevolutionized the field of protein engineering. Key elementsof such methods are the various ways in which the genotypes(the genes) and the phenotypes (the encoded proteins) arephysically linked during the process. LÄS MER
4. Engineering of Human Fetal Hemoglobin
Sammanfattning : In blood, the oxygen-transporting protein hemoglobin (Hb) governs the oxygenation of cells and tissues. Naturally, this protein has claimed a place in the center of the research field of artificial oxygen therapeutics. LÄS MER
5. Protein Mixture Inference as Hitting Set Variants and Linear Algebra Problems
Sammanfattning : This work is dedicated to the problems of protein inference and quantification in bottom-up proteomics, and, in particular, in shotgun proteomics. We adopt a rather classical approach of representing inference problem as a set cover, where proteins are understood as sets of their observations: peptides' masses or sequences. LÄS MER