Sökning: "paralogues"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet paralogues.

  1. 1. Olfactory genomics of bark- and ambrosia beetles : Evolution and function of chemoreceptors

    Författare :Twinkle Biswas; Feromongruppen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Curculionidae; functional characterisation; odorant receptors ORs ; gustatory receptors; ionotropic receptors; orthologues; paralogues; olfactory sensory neurons; OR-ligand interaction;

    Sammanfattning : Insect behaviours, such as host and mate selection, are often mediated by chemical cues. The chemical cuesare detected by large and rapidly evolving families of chemoreceptors which include odorant receptors (ORs),gustatory receptors (GRs) and ionotropic receptors (IRs). LÄS MER

  3. 2. Processing of the amyloid precursor protein and its paralogues amyloid precursor-like proteins 1 and 2

    Författare :Linda Adlerz; Kerstin Iverfeldt; Richard Cowburn; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APP; APLP1; APLP2; Alzheimer s disease; Amyloid β-peptide; Processing; RA; BDNF; IGF-1; curcumin; PI3-K; MAPK; cdk5; Neurochemistry; Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Sammanfattning : Alzheimer’s disease (AD) is a neurodegenerative disorder which is histopathologically characterised by amyloid plaques and neurofibrillary tangles. Amyloid plaques consist of the amyloid β-peptide (Aβ) that can form aggregates in the brain. Aβ is generated from the amyloid precursor protein (APP) through proteolytic cleavage. LÄS MER

  4. 3. Hypoxia inducible factor 1alpha : molecular mechanisms of regulation

    Författare :William J Wilson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hypoxia-Inducible Factor 1alpha (HIF-1alpha) is an important protein in the homeostatic control of genes in response to low oxygen, or hypoxia. It is thus also a key factor in the regulation of angiogenesis in response to hypoxia, including induction of vascular endothelial growth factor (VEGF) gene expression. LÄS MER

  5. 4. Disentangling the Reticulate History of Polyploids in Silene (Caryophyllaceae)

    Författare :Magnus Popp; Bengt Oxelman; Magnus Lidén; Jeff J. Doyle; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Silene; Sileneae; polyploidy; low copy nuclear DNA; RNA polymerase; RPA2; RPB2; RPD2; internal transcribed spacer; rps16; psbE-petL; concerted evolution; reticulate evolution; lineage sorting; Biologi; Biology; Biologi;

    Sammanfattning : DNA sequences from the rps16 intron and the psbE-petL spacer from the chloroplast genome, the ribosomal nuclear ITS region, and introns from the low copy nuclear genes RPA2, RPB2, RPD2a and RPD2b, are in different combinations used to infer phylogenetic relationships in Sileneae (Caryophyllaceae). Used in concert, the biparentally inherited nuclear regions are useful to distinguish between paralogy due to allopolyploidy and single gene duplications, respectively, because the latter are not expected to give rise to repeated phylogenetic patterns in potentially unlinked sequence regions. LÄS MER

  7. 5. Identification of molecular markers associated with fungal resistance in Norway spruce and common ash

    Författare :Rajiv Chaudhary; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Trees are giants of the forests, possessing nutrient-rich tissues that make them natural targets for pathogens. In Europe, the fungal pathogens Heterobasidion annosum s.l. and Hymenoscyphus fraxineus are associated with Norway spruce and common ash, respectively. LÄS MER