Sökning: "orthologues"

Visar resultat 1 - 5 av 25 avhandlingar innehållade ordet orthologues.

  1. 1. Olfactory genomics of bark- and ambrosia beetles : Evolution and function of chemoreceptors

    Författare :Twinkle Biswas; Feromongruppen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Curculionidae; functional characterisation; odorant receptors ORs ; gustatory receptors; ionotropic receptors; orthologues; paralogues; olfactory sensory neurons; OR-ligand interaction;

    Sammanfattning : Insect behaviours, such as host and mate selection, are often mediated by chemical cues. The chemical cuesare detected by large and rapidly evolving families of chemoreceptors which include odorant receptors (ORs),gustatory receptors (GRs) and ionotropic receptors (IRs). LÄS MER

  3. 2. Atypical Solute Carriers : Identification, evolutionary conservation, structure and histology of novel membrane-bound transporters

    Författare :Emelie Perland; Robert Fredriksson; Helgi Schiöth; Åsa Mackenzie; Sonchita Bagchi; Carsten Uhd Nielsen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Major facilitator superfamily; solute carrier; transporter; protein expression; mRNA expression; phylogenetic clustering; orthologues; co-expression; subcellular location; nutrition.; Neuroscience; Neurovetenskap;

    Sammanfattning : Solute carriers (SLCs) constitute the largest family of membrane-bound transporter proteins in humans, and they convey transport of nutrients, ions, drugs and waste over cellular membranes via facilitative diffusion, co-transport or exchange. Several SLCs are associated with diseases and their location in membranes and specific substrate transport makes them excellent as drug targets. LÄS MER

  4. 3. Structural Insight into the Bacterial Sialic Acid Catabolic Pathway

    Författare :Rhawnie Caing Carlsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sialic acid; bacterial catabolic pathway;

    Sammanfattning : A genetically diverse community of commensal and pathogenic bacteria thrive in the digestive system and urogenital tracts of animals. Many of these bacteria forage sialic acid from mucosal cell surfaces. LÄS MER

  5. 4. Characterization of Novel Solute Carriers in Humans, Mice and Flies : Solute Carriers in a Broad and Narrow Perspective

    Författare :Mikaela Ceder; Robert Fredriksson; Anita Öst; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Solute carrier; SLC; Putative SLCs; Major facilitator superfamily; MFS; Drosophila melanogaster; Glucose metabolism; UNC93A; CG4928; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The solute carrier family is the largest family of membrane-bound transporters in humans, with 430 members divided into 65 subfamilies. They transport various substrates across lipid barriers and are vital for absorption, distribution, metabolism and excretion in all cell types in the body. LÄS MER

  7. 5. Cloning and characterization of neuropeptide Y receptors of the Y1 subfamily in mammals and fish

    Författare :Paula Starbäck; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein; neuropeptide Y; panacreatic polypeptide; neuropeptide Y receptor; ortholog; zebrafish; guinea pig; pseudogene; evolution; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Sammanfattning : Neuropeptide Y (NPY) is an abundant neurotransmitter in the nervous system and forms a family of evolutionarily related peptides together with peptide YY (PYY), pancreatic polypeptide (PP) and polypeptide Y (PY). These peptides are ligands to a family of receptors that mediate a wide range of physiological effects including stimulation of appetite. LÄS MER