Sökning: "pancreatic tumors"

Visar resultat 1 - 5 av 70 avhandlingar innehållade orden pancreatic tumors.

  1. 1. Pancreatic Neuroendocrine Tumors : Surgical Treatment and Follow-up

    Författare :Josefine Kjaer; Olov Norlén; Kjetil Soreide; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pancreatic neuroendocrine tumor; surgery; liver metastases; hepatic resection; liver transplantation; recurrence; Kirurgi; Surgery;

    Sammanfattning : Pancreatic neuroendocrine tumors (Pan-NET), are rare, heterogenous and derive from the hormone producing cells in the pancreas. The functioning tumors that overproduce hormones cause clinical syndromes with specific symptoms due to the hormonal production. LÄS MER

  3. 2. Current Medical Treatment of Endocrine Pancreatic Tumors and Future Aspects

    Författare :Marie-Louise Fjällskog; Morten Vatn; Uppsala universitet; []
    Nyckelord :Medical sciences; pancreatic tumors; somatostatin analogs; cisplatin; etoposide; somatostatin receptors; immunohistochemistry; tyrosine kinase receptors; platelet-derived growth factors receptors PDGFRs ; c-kit; epidermal growth factor receptor EGFR ; MEDICIN OCH VÅRD; alfa-interferon; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : We treated 16 patients with somatostatin analogs combined with α-interferon and achieved a biochemical and/or radiological response in 56% (median duration 22 months). We consider this treatment a good alternative for patients who fail during chemotherapy or who do not want to/cannot receive cytotoxic drugs. LÄS MER

  4. 3. Theranostics in Neuroendocrine Tumors : Somatostatin Receptor Imaging and Therapy

    Författare :Ezgi Ilan; Mark Lubberink; Peter Bernhardt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 177Lu-DOTATATE; 68Ga-DOTATATE; 68Ga-DOTATOC; PRRT; Theranostics; PET CT; SPECT CT; Neuroendocrine tumors; Somatostatin receptors; Medicinsk radiofysik; Medical Radiophysics;

    Sammanfattning : Neuroendocrine tumors (NETs) are characterized by cellular overexpression of somatostatin receptors (SSTR), which allows for the use of radiolabeled somatostatin analogs (SSA) for both imaging and therapy. Because NETs often are diagnosed at a metastatic stage, curative surgery is not possible. LÄS MER

  5. 4. Advances in the Perioperative Management of Pancreatic Cancer

    Författare :Srinivas Sanjeevi; Christoph Ansorge; Sara Regnér; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; pancreatic ductal adenocarcinoma; prophylactic double bypass; pancreaticojejunostomy; neoadjuvant chemotherapy; post-operative pancreatic fistula; Kirurgi; Surgery;

    Sammanfattning : Surgery is currently the only form of curative treatment for pancreatic cancer, yet five-year survival rates following resection are just 15-20%. Improved hospital care has decreased postoperative mortality to 2% yet morbidity remains high at 50%. Poor survival and high morbidity are driven by several perioperative factors. LÄS MER

  7. 5. Genetic studies of endocrine abdominal tumors

    Författare :Ola Hessman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; MEN1; LOH; pancreatic endocrine tumors; midgut carcinoid; Smad4 DPC4; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Sammanfattning : Pancreatic endocrine tumors (PETs) occur sporadically or in the familial multiple endocrine neoplasia type 1 (MEN1) syndrome, whereas midgut carcinoids are nonfamilial, malignant endocrine tumors of the intestine. For these tumor entities morphological criteria are of limited use for prognostic prediction and selection of treatment. LÄS MER