Sökning: "outer membrane vesicles"

Visar resultat 6 - 10 av 36 avhandlingar innehållade orden outer membrane vesicles.

1. 6. Host-Pathogen Interactions in Pseudomonas aeruginosa Invasive and Respiratory Tract Infection

   Författare :Magnus Paulsson; Malmö Klinisk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseudomonas aeruginosa; vitronectin; Respiratory tract infections; Innate Immunity; outer membrane vesicles; outer membrane proteins; beta-lactamase; ciprofloxacin; combination treatment; bacteraemia; Complement escape;

   Sammanfattning : Pseudomonas aeruginosa is an opportunistic bacterium that causes debilitating infections when the immune defence is compromised. It possesses an arsenal of virulence traits to colonize most compartments of the body and is often highly resistant against commonly used antimicrobial drugs. LÄS MER

3. 7. Protein production in the E. coli cell envelope

   Författare :Thomas Baumgarten; Jan-Willem de Gier; Dirk-Jan Scheffers; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; E. coli; protein biogenesis; recombinant proteins; membrane proteins; secretory proteins; protein displays; outer membrane vesicles; Biochemistry; biokemi;

   Sammanfattning : Proteins fulfil essential functions in every cell and malfunctioning proteins are often the cause of diseases. On the other hand, proteins like antibody fragments or hormones can be used to treat diseases. LÄS MER

4. 8. Hydrodynamic flow for deterministic sorting of cell-membrane components

   Författare :Björn Johansson Fast; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Gold nanoparticles; Diffusion; Microfluidics; Native membrane vesicles; Single particle tracking; Protein enrichment; Hydrodynamic forces; Supported lipid bilayer; Size determination;

   Sammanfattning : The biological membrane, an amphiphilic structure that is the barrier between the cell interior and exterior, is one of the vital building blocks of all cells. Not only does it define the outer boundaries of the cell, it also carries important biological function by virtue of the proteins and other molecules that constitute the membrane, the function of which is in turn intimately coupled to their association with the lipid-based membrane. LÄS MER

5. 9. Insight into the mitochondrial apoptotic pathway : The interplay of the pro-apoptotic Bax protein with oxidized phospholipids and its counterplayer, the pro-survival Bcl-2 protein

   Författare :Marcus Wallgren; Gerhard Gröbner; Marco Colombini; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; apoptosis; Bax; Bcl-2; CD; cell-free protein synthesis; DSC; membrane; mitochondria; oxidized phospholipids; reconstitution; solid state NMR; biologisk kemi; biological chemistry;

   Sammanfattning : Apoptosis plays a crucial role in multicellular organisms by preserving tissue homeostasis and removing harmful cells. The anti-apoptotic B-cell CLL/lymphoma 2 (Bcl-2) and the pro-apoptotic Bcl-2-associated X protein (Bax) act as major regulators of the mitochondrial apoptotic pathway. LÄS MER

7. 10. Vesicle-mediated and free soluble delivery of bacterial effector proteins by oral and systemic pathogens

   Författare :Bernard Thay; Jan Oscarsson; Mikael Rhen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Periodontitis; Aggregatibacter actinomycetemcomitans; Staphylococcus aureus; membrane vesicles; vesicle-host cell interaction; protein delivery; molekylärbiologi; Molecular Biology;

   Sammanfattning : Periodontitis, the primary cause of tooth-loss worldwide, is a bacterially induced chronic inflammatory disease of the periodontium. It is associated with systemic conditions such as cardiovascular disease (CVD). However, pathogenic mechanisms of periodontitis-associated bacteria that may contribute to the CVD association are unclear. LÄS MER