Sökning: "missing at random MAR"

Hittade 2 avhandlingar innehållade orden missing at random MAR.

  1. 1. Methodology for Handling Missing Data in Nonlinear Mixed Effects Modelling

    Författare :Åsa M. Johansson; Mats O. Karlsson; Andrew C. Hooker; Leon Aarons; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; population models; censored observations; missing covariates; missing dependent variable; missing data mechanism; missing completely at random MCAR ; missing at random MAR ; missing not at random MNAR ; estimation algorithms; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : To obtain a better understanding of the pharmacokinetic and/or pharmacodynamic characteristics of an investigated treatment, clinical data is often analysed with nonlinear mixed effects modelling. The developed models can be used to design future clinical trials or to guide individualised drug treatment. LÄS MER

  3. 2. Uncertainty intervals and sensitivity analysis for missing data

    Författare :Minna Genbäck; Xavier de Luna; Elena Stanghellini; Arvid Sjölander; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; missing data; missing not at random; non-ignorable; set identification; uncertainty intervals; sensitivity analysis; self reported health; average causal effect; average causal effect on the treated; mixed-effects models; Statistics; statistik;

    Sammanfattning : In this thesis we develop methods for dealing with missing data in a univariate response variable when estimating regression parameters. Missing outcome data is a problem in a number of applications, one of which is follow-up studies. LÄS MER