Sökning: "membrane orientation"

Visar resultat 21 - 25 av 55 avhandlingar innehållade orden membrane orientation.

  1. 21. Exploring the Molecular Dynamics of Proteins and Viruses

    Författare :Daniel Larsson; David van der Spoel; Modesto Orozco; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molecular dynamics; virus dynamics; capsid dissolution; satellite tobacco necrosis virus; satellite tobacco mosaic virus; virus genome structure; gas phase protein structure; water layer; micelle embedded protein; membrane protein; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Sammanfattning : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. LÄS MER

  3. 22. Cell-protein-material Interactions on Bioceramics and Model Surfaces

    Författare :Åsa Rosengren; Sven Oscarsson; Lucy Di Silvio; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; protein adsorption; blood proteins; biomaterials; ceramics; glass-ceramics; two-dimensional gel electrophoresis; protein orientation; silicon wafers; atomic force microscopy; bone cell adhesion; divalent cation dependency; Kemi; Chemistry; Kemi;

    Sammanfattning : The objective of this thesis was to investigate and characterize the interaction between blood proteins and different surfaces with emphasis on protein adsorption to bioceramics and model surfaces. Special effort was made to monitor the spontaneous and selective adsorption of proteins from human plasma and to examine the orientation, conformation and functional behavior of single proteins after adsorption. LÄS MER

  4. 23. Exploring Unorthodox Aquaporins : Characterization of NbXIPs & AtNIPs

    Författare :Henry Ampah-Korsah; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Aquaporins; XIPs; NIPs; Phosphorylation; Pichia pastoris; Overexpression; boric acid; membrane proteins;

    Sammanfattning : AbstractAquaporins are membrane integral proteins that facilitate the transport of waterand/or other small neutral molecules across biological membranes in cells in allforms of life. Among the subfamilies of aquaporins in higher plants, the X IntrinsicProteins (XIPs) are the most recently discovered subfamily and the leastcharacterized. LÄS MER

  5. 24. Design and synthesis of glycose-derivatives and related molecules for cell membrane mimetics

    Författare :Jing Shi; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : A series of glucopyranose (α-D-glucose, β-D-glucose, D-gluconic acid and 6-amino-6-deoxy-D-glocuse) terminated alkanethiol acetals have been successfully synthesized. α and β-D-glucose were configured in controlled ways coupling with alkanethiol, in which bromosugar and trichloroacetirnidates were selected as activated glycosyl donors using different promoters tetraalkylammonium bromide (Et4NBr) and trimethylsilanetriflate (TMSOTf) respectively. LÄS MER

  7. 25. Colon cancer specific cytochrome P450 2W1 : polymorphism, membrane topology and endogenous roles in development

    Författare :Jia Guo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cytochrome P450 2W1 (CYP2W1) belongs to a family of drug metabolizing monooxygenases with an unidentified yet endogenous function. CYP2W1 expression pattern has characteristic features of oncofetal genes. Previous studies have shown significant levels of CYP2W1 protein in 30% of human colon cancers and in 50% of corresponding liver metastases. LÄS MER