Sökning: "lipid"

Visar resultat 26 - 30 av 1492 avhandlingar innehållade ordet lipid.

  1. 26. 3D printing of lipid-based formulations into personalized solid oral dosage forms

    Författare :Jenny Johannesson; Christel Bergström; Alexandra Teleki; Mattias Paulsson; Maria Strömme; Abdul Basit; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; poorly water-soluble drug; lipid-based formulation; Pickering emulsion; emulsion gel; semi-solid extrusion; 3D printing; lipid tablet; personalized dosage form; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The pharmaceutical development process starts with patient populations and their unmet therapeutic needs. Traditional pharmaceutical manufacturing of solid oral dosage forms is based on the strategy of one-size-fits-all. This is problematic, especially for patient populations with high patient-to-patient variability, as in pediatrics. LÄS MER

  3. 27. A theoretical study of 5-Aminolevulinic acid and its esters : properties and lipid permeability

    Författare :Edvin Erdtman; Leif Eriksson; Fahmi Himo; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysical chemistry; Biofysikalisk kemi; fysikalisk kemi; Physical Chemistry;

    Sammanfattning : 5-aminolevulinic acid (5ALA) is a widely used prodrug in Photodynamic therapy (PDT). The target molecule in 5ALA-PDT is Protoporphyrin IX (PpIX), which is synthesized endogenously via the heme pathway in the cell. LÄS MER

  4. 28. Molecular Dynamics Simulations of Fluid Lipid Membranes

    Författare :Erik G. Brandt; Olle Edholm; Mats Wallin; Markus Deserno; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biological fluid dynamics; biomembranes; hydrodynamics; lipid bilayers; molecular dynamics; neutron spin echo;

    Sammanfattning : Lipid molecules form thin biological membranes that envelop all living cells, and behave as two-dimensional liquid sheets immersed in bulk water. The interactions of such biomembranes with their environment lay the foundation of a plethora of biological processes rooted in the mesoscopic domain - length scales of 1-1000 nm and time scales of 1-1000 ns. LÄS MER

  5. 29. Exploring the Interactive Landscape of Lipid Bilayers

    Författare :Christian L. Wennberg; Erik Lindahl; Arnold Maliniak; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular Dynamics; lipid bilayer; cholesterol; permeability; long-range interactions; Lennard-Jones; dispersion; particle-mesh Ewald; Biological Physics; Biologisk fysik;

    Sammanfattning : One of the most important aspects for all life on this planet is theact to keep their cellular processes in a state where they do notreach equilibrium. One part in the upholding of this imbalanced stateis the barrier between the cells and their surroundings, created bythe cell membrane. LÄS MER

  7. 30. Systems Biology of Yeast Lipid Metabolism

    Författare :Pramote Chumnanpuen; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Transcriptome; Integrated analysis; Lipidome.; Inositol-choline; Opi1; Yeast lipid metabolism; high throughput techniques; Ino4; TORC1; Snf1; Ino2;

    Sammanfattning : Lipid metabolism plays an important role in the development of many different life-style related diseases, such as type 2 diabetes and atherosclerosis, and understanding the molecular mechanisms behind regulation of lipid biosynthesis and degradation may lead to development of new therapies. In this project we undertook a global study of lipid metabolism in the eukaryotic model organism Saccharomyces cerevisiae. LÄS MER