Sökning: "Yeast lipid metabolism"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Yeast lipid metabolism.

  1. 1. Systems Biology of Yeast Lipid Metabolism

    Författare :Pramote Chumnanpuen; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Transcriptome; Integrated analysis; Lipidome.; Inositol-choline; Opi1; Yeast lipid metabolism; high throughput techniques; Ino4; TORC1; Snf1; Ino2;

    Sammanfattning : Lipid metabolism plays an important role in the development of many different life-style related diseases, such as type 2 diabetes and atherosclerosis, and understanding the molecular mechanisms behind regulation of lipid biosynthesis and degradation may lead to development of new therapies. In this project we undertook a global study of lipid metabolism in the eukaryotic model organism Saccharomyces cerevisiae. LÄS MER

  2. 2. Engineering Lipid Metabolism for Production of Oleochemicals in Saccharomyces cerevisiae

    Författare :Paulo Teixeira; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; TEKNIK OCH TEKNOLOGIER; NATURAL SCIENCES; ENGINEERING AND TECHNOLOGY; oleochemicals; lipid homeostasis; Saccharomyces cerevisiae; lipid metabolism;

    Sammanfattning : Oleochemicals are chemicals usually derived from plant oils or animal fat. Large use of plant oil derivatives as replacements for petroleum-derived chemicals brings sustainability issues from extensive cultivation of oil plants in restricted regions. LÄS MER

  3. 3. Development of Nonlinear Microscopy for Studies of Metabolism and Tissue Engineering

    Författare :Madeleine Åkeson; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; imaging; bacterial cellulose; nonlinear microscopy; Saccharomyces cerevisiae; yeast; C. elegans; Microscopy; lipid storage;

    Sammanfattning : Nonlinear microscopy techniques provide abilities for noninvasive and selective imaging of structural and chemical properties of biological systems. These techniques include coherent anti-Stokes Raman scattering (CARS) microscopy with the ability to selectively image molecular vibrations, second harmonic generation (SHG) microscopy which selectively images fiber structures, and third harmonic generation (THG) microscopy which is sensitive to interfaces between materials with different optical properties. LÄS MER

  4. 4. Engineering cytosolic acetyl-CoA metabolism in Saccharomyces cerevisiae

    Författare :Yiming Zhang; Chalmers University of Technology; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; reverse engineering; flavodoxin; genomic DNA sequencing; ferredoxin; histone deacetylase; adaptive evolution; ferredoxin flavodoxin NADP reductase; pyruvate decarboxylase; citrate synthase; hexose transporter; yeast; mitochondria; aerobic growth; metabolic engineering.; acetyl-CoA; central carbon metabolism;

    Sammanfattning : A Saccharomyces cerevisiae strain carrying deletions in all three pyruvate decarboxylase genes (also called Pdc negative yeast) represents a non-ethanol producing platform strain for biochemical production. However, it cannot grow on glucose as the sole carbon source due to the lack of cytosolic acetyl-CoA for lipid biosynthesis. LÄS MER

  5. 5. Advancing CRISPR technologies to engineer yeast metabolism

    Författare :Raphael Ferreira; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; oleochemicals; metabolic engineering; Saccharomyces cerevisiae; CRISPR;

    Sammanfattning : The advent of genetic engineering tools has initiated an era of manipulating microorganisms for the production of valuable compounds for our society. Precise engineering of these microbes commonly requires introducing genetic modifications such as gene deletion, overexpression, and accurate regulation in order to enhance the production of the compound of interest. LÄS MER