Sökning: "lipid metabolism"

Visar resultat 16 - 20 av 404 avhandlingar innehållade orden lipid metabolism.

  1. 16. Lipid metabolism in the pancreatic beta-cell. Implications for insulin secretion

    Författare :Malin Fex; Celiaki och diabetes; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; Lipid metabolism; Insulin secretion; Beta-cells;

    Sammanfattning : We have investigated the role of lipid metabolism with regard to beta-cell function and insulin secretion. Lipids are known to play a crucial functional role in the pancreatic beta-cell, where they are essential for adequate hormone release, but may also exert a long-term toxic effect, leading to beta-cell dysfunction. LÄS MER

  3. 17. PPARs in the regulation of gene expression and lipid metabolism in the liver

    Författare :Ulrika Edvardsson; Göteborgs universitet; []
    Nyckelord :PPARalpha; PPARgamma; PPARgamma2; Wy14; 643; rosiglitazone; liver; hepatocytes; insulin; fatty acids; MTP; ADRP; lipid metabolism; apoB; triglycerides.;

    Sammanfattning : Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors, regulating genes involved in carbohydrate, lipid and lipoprotein metabolism. Synthetic PPARalpha agonists used in clinic are the fibrates, and their hypotriglyceridemic effect is believed to be the result of decreased VLDL triglyceride secretion and increased turnover of triglyceride-rich lipoprotein particles in the circulation. LÄS MER

  4. 18. Effects of early probiotic supplementation in a pediatric setting : Focus on body composition, metabolism and inflammation

    Författare :Frida Karlsson Videhult; Christina E West; Olle Hernell; Inger Öhlund; Velmurugesan Arulampalam; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lactobacillus paracasei ssp. paracasei F19; infants; children; growth; body composition; metabolism; follow-up; Pediatrics; pediatrik;

    Sammanfattning : We aimed to determine the short- and long-term effects on growth, body composition, metabolic and inflammatory markers following supplementation with the probiotic Lactobacillus paracasei ssp. paracasei F19 (LF19) during weaning. LÄS MER

  5. 19. Myocardial metabolism in experimental infarction and heart failure

    Författare :Truls Råmunddal; Göteborgs universitet; []
    Nyckelord :Myocardial metabolism; Heart failure; Myocardial infarction; Lipotoxic heart disease; Apolipoprotein B; Arrhythmias; Cardiac reserve; Creatine metabolism;

    Sammanfattning : Abstract The heart is an organ heavily dependent on exogenous lipids for the oxidative production of adenosine-triphosphate (ATP) and therefore maintenance of normal cellular energy homeostasis. However, high energy flux organs such as the heart must closely match lipid import and utilization or otherwise lipids will accumulate in the cardiomyocytes. LÄS MER

  7. 20. The role of GH in the regulation of energy homeostasis, lipid metabolism and cardiovascular function in transgenic mice

    Författare :Bob Olsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth hormone; cardiovascular disease; energy homeostasis; lipid metabolism; transgenic mice;

    Sammanfattning : The aim of this thesis was, using two transgenic models, to investigate some metabolic diseases associated with acromegaly e.g. hypertension and alterations in lipid and lipoprotein metabolism. LÄS MER