Sökning: "ketone"

Visar resultat 11 - 15 av 67 avhandlingar innehållade ordet ketone.

1. 11. X-ray structure analysis of short-chain dehydrogenases/reductases

   Författare :Jordi Benach-Andreu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :crystal structure; short-chain dehydrogenases reductases; Drosophila alcohol dehydrogenase; catalytic reaction mechanism; Comamonas testosteroni 3[beta] 17[beta]hydroxysteroid dehydrogenase;

   Sammanfattning : X-ray crystallography and site-directed mutagenesis were used to better understand the structure/function relationships in the family of short-chain dehydrogenases/reductases (SDR). This group of enzymes constitutes a protein family with at least 60 members with highly diverse functions in pro- and eukaryotes. LÄS MER

3. 12. Palladium-catalyzed lignin valorization : Towards a lignin-based biorefinery

   Författare :Maxim Galkin; Joseph Samec; Rafael Luque; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Lignin; Heterogeneous Catalysis; Palladium; Biomass; Depolymerization; Reduction; Oxidation; Biorefinery; Transfer Hydrogenolysis; Organic Chemistry; Organisk kemi;

   Sammanfattning : The work described in this thesis focuses on the cleavage of the β-O-4′ bond, which is the most abundant interunit linkage in the lignin polymer.In the first part, three methods based on palladium catalysis have been developed and their applicability has been verified using lignin model compounds. LÄS MER

4. 13. Syntheses of functionalized Phe-Gly dipeptidomimetics

   Författare :Wei Berts; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

   Sammanfattning : The complete series of Boc-protected C-4 mono- and difluoroallyl Phe-Gly dipeptidomimetics and their corresponding saturated derivatives has been synthesized. A mechanism that rationalizes the formation of the two isomeric allylic mono-fluorides from an allylic alcohol with diethylaminosulfur trifluoride (DAST) has been investigated. LÄS MER

5. 14. Oxidation of Ketones: A (Chemo-) Enzymatic Approach Using Oxygenases and Hydrolases

   Författare :Georgina Chávez; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cross linked enzyme aggregates.; caprolactone; perhydrolase; Lipase B from Candida antarctica;

   Sammanfattning : Oxidation reactions are important in organic chemistry as well as in nature. In industry, oxidations are commonly used for the synthesis of chemicals and pharmaceuticals, however such processes have a number of limitations, they use chlorinated solvents, stoichiometric oxidation reagents, and in some cases the reagents that have risks of explosion during transportation and storage. LÄS MER

7. 15. Experimental studies of kinetic solvent deuterium isotope effects on proton abstraction in alcohol solution

   Författare :Jan-Olof Levin; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : The present dissertation is an account based on investigations published in the following papers:I. JAN-OLGF LEVIN and CHRISTOFFER RAPPE, Solvent Deuterium Isotope Effects in Alcohols. I. Racemization of Phenyl2,2-Diphenylcyclopropyl Ketone, 3-Nethyl-4-phenyl-2-butanone and 2-Nethyl-1-indanone. LÄS MER