Sökning: "Comamonas testosteroni 3[beta] 17[beta]hydroxysteroid dehydrogenase"

Hittade 2 avhandlingar innehållade orden Comamonas testosteroni 3[beta] 17[beta]hydroxysteroid dehydrogenase.

  1. 1. X-ray structure analysis of short-chain dehydrogenases/reductases

    Författare :Jordi Benach-Andreu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :crystal structure; short-chain dehydrogenases reductases; Drosophila alcohol dehydrogenase; catalytic reaction mechanism; Comamonas testosteroni 3[beta] 17[beta]hydroxysteroid dehydrogenase;

    Sammanfattning : X-ray crystallography and site-directed mutagenesis were used to better understand the structure/function relationships in the family of short-chain dehydrogenases/reductases (SDR). This group of enzymes constitutes a protein family with at least 60 members with highly diverse functions in pro- and eukaryotes. LÄS MER

  2. 2. Short-chain dehydrogenases/reductases : structure, function and motifs of hydroxysteroid dehydrogenases

    Författare :Charlotta Filling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Short-chain dehydrogenases reductases; site-directed mutagenesis; steady-state kinetics; X-ray structure; enzyme function; steroid; motif; reaction mechanism; 3 beta 17 beta-hydroxysteroid dehydrogenase; 17 beta-hydroxysteroid dehydrogenase; short chain hydroxyacyl coenzyme A dehydrogenase;

    Sammanfattning : Short-chain dehydrogenases/reductases (SDR) constitute a superfamily of proteins catalysing reactions of a wide range of substrates in all life forms. During the past years, a large number of new proteins belonging to this superfamily has been detected. They are important in e.g. LÄS MER