Sökning: "internalization"

Visar resultat 21 - 25 av 172 avhandlingar innehållade ordet internalization.

  1. 21. Papillomavirus binding and entry : The heparan sulfate receptor and inhibition by lactoferrin

    Författare :Peter Drobni; Umeå universitet; []
    Nyckelord :;

    Sammanfattning : Papillomaviruses (PVs) infect epithelial cells and are the main causative agent of cervical carcinoma. There are today more than a hundred different PV types and these can be divided into high risk and low risk types. They infect differentiating epithelial cells which make it cumbersome to propagate and produce human papillomavirus (HPV) virions. LÄS MER

  3. 22. Interaction between extracellular adherence protein (Eap) from Staphylococcus aureus and the human host

    Författare :Axana Haggar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Staphylococcus aureus is one of the most common agents causing bacterial infections in humans and animals. The emergence of extended antibiotic resistance among S. aureus strains as a worldwide epidemic has driven the development of alternative strategies to combat this microorganism. LÄS MER

  4. 23. The Role of Membrane Trafficking in G Protein-Coupled Receptor Regulation

    Författare :Johan Enquist; Drug Target Discovery; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; downregulation; recycling; resensitization; desensitization; GPCR; membrane trafficking;

    Sammanfattning : Movements of a receptor in the plasma membrane and within the cell influence receptor function and physiology. I have investigated the role of such movements, generally known as membrane trafficking, in G protein-coupled receptor regulation. LÄS MER

  5. 24. Virulence mechanisms of two gram negative bacteria : studies on Escherichia coli hemolysin HlyA and on the interaction of Brucella abortus with non-phagocytic cells

    Författare :Caterina Guzman-Verri; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Virulence factors may be classified in two general groups: those that cause damage to the host and those that promote bacterial colonization and invasion. In this study, the tissue damaging Escherichia coli hemolysin HlyA and the mechanism of internalization of the intracellular parasite Brucella abortus were investigated. LÄS MER

  7. 25. Innovation outside: When spin-off firms and developer communities change the boundaries of the firm

    Författare :Martin Wallin; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; free and open source software; external venturing; organization of innovation; spin-off; Sweden; developer communities; resource-based theory of the firm; innovation outside; open innovation;

    Sammanfattning : Few observers dispute that innovation is at the very heart of economic development and prosperity and a key determinant for the competitiveness of firms. Yet the literature has found it challenging to incorporate the boundary-spanning characteristic of innovation into the theory of the firm. LÄS MER