Sökning: "integrins"

Visar resultat 31 - 35 av 124 avhandlingar innehållade ordet integrins.

1. 31. Dynamics of LFA-1 in T lymphocytes

   Författare :Malin Samuelsson; Leukocyt migration; []
   Nyckelord :T lymphocytes; adhesion; migration; integrins; LFA-1; regulation; recycling; Rab; RhoB; PTPN22;

   Sammanfattning : .... LÄS MER

3. 32. Functions of integrin receptors in extravascular neutrophil migration and respiratory burst

   Författare :Joachim Werr; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :adhesion molecules; leukocyte migration; neutrophils; chemotaxis; integrins; respiratory burst; leukocyte extravasation; extracellular matrix; intravital microscopy; acute inflammation;

   Sammanfattning : Leukocytes circulate in the vasculature, but, must leave the blood stream and migrate through the surrounding tissue to exert their protective functions in inflammation. Numerous studies have revealed that intravascular leukocyte-endothelial cell interactions involve functions of adhesion molecules belonging to the selectin and integrin receptor families. LÄS MER

4. 33. The diverse role of laminin isoforms in neuronal cells, human mast cells and blood platelets

   Författare :Wondossen Sime; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Laminins; extracellular matrix; integrins; tooth pulp fibroblasts; mast cells; megakaryocytes; platelets; cell adhesion; cell migration; neurite outgrowth;

   Sammanfattning : The close interaction of cells with other cells and with extracellular matrix (ECM) components is a prerequisite in a number of biological activities. During development of the nervous system, axons often navigate a considerable distance depending on the type of molecular factors they encounter. LÄS MER

5. 34. Interaction of human blood platelets, lymphocytes and monocytes with vascular laminin isoforms

   Författare :Gezahegn Gorfu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Vascular laminin isoforms; extracellular matrix; integrins; cell adhesion; cell migration; high endothelial venules; lymphocytes; monocytes; platelets; leukocyte extravasation;

   Sammanfattning : Inflammatory and immune responses play a fundamental role in both health and disease, and leukocytes are important actors in these processes. Migration of the leukocytes to sites of injury or inflammation is a crucial component of innate and adaptive immunity. It is currently accepted that leukocyte extravasation is a multistep process. LÄS MER

7. 35. Leukocyte rolling and firm adhesion in the microvasculature : functional significance for leukocyte recruitment in inflammation

   Författare :Xun Xie; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :adhesion molecules; blood flow; chemoattractants; endothelium; flowcytometry; fucoidin; heparin; inflammation; integrins; intravital microscopy; leukocyteadhesion; leukocyte extravasation; leukocyte rolling; meningitis; mesentery; microcirculation; ;

   Sammanfattning : Leukocyte recruitment to tissues is a key component in the inflammatory process. In order for circulating leukocytes to extravasate, they need to interact with vascular endothelium in several sequential steps. LÄS MER