Sökning: "integrins"
Visar resultat 21 - 25 av 124 avhandlingar innehållade ordet integrins.
21. Signaling capacity of ß2-integrins in relations to neutrophil motility
Sammanfattning : The neutrophil granulocyte is one of the most mobile cell types in the human body and represents the first line of defense against invading pathogens. Adhesion and chemotactic receptors on the cell surface work together through modulations of the cytoskeleton and thereby cause the cell to move. LÄS MER
22. The role of 1-intergrins in skeletal muscle differentiation and extracellular matrix assembly
Sammanfattning : Integrin subunit β1 forms heterodimeric receptors with at least 12 different α-subunits.These integrins are the main cellular receptors for extracellular matrix and they arenecessary for normal development. In this thesis, the effects of lack of integrin subunitβ1 on matrix deposition and on skeletal muscle development were studied. LÄS MER
23. Cell-matrix interactions in neuronal regeneration : focus on integrins and laminins
Sammanfattning : The central and peripheral nervous system (CNS and PNS, respectively) differ in their ability to regenerate after injury. This difference has been attributed both to intrinsic differences in the properties of the neurons and to the extracellular environment. LÄS MER
24. Functional and structural characterization of integrins and their ligands ICAM-2, vitronectin and fibronectin in leukocytes
Sammanfattning : Transient adhesion of leukocytes to cells and extracellular matrices is a crucial process in leukocyte physiology. Cell surface adhesion molecules such as integrins and members of the immunoglobulin (Ig) superfamily are involved. LÄS MER
25. Studies of Mesenchymal Progenitor Cells and Tumour Growth, Integrins and Matrix Metalloproteinases
Sammanfattning : In this thesis we characterize the effect of mesenchymal progenitor cells (MPCs) on tumour growth, and show that MPCs can have inhibitory effects on tumour development. We developed a method to subcutaneously transplant tumour cells, cultured in vitro in a pre-formed gelatin matrix, that made it possible to study the early phases of tumour development. LÄS MER