Sökning: "inflammatory rheumatic disease"

Visar resultat 6 - 10 av 66 avhandlingar innehållade orden inflammatory rheumatic disease.

  1. 6. Complement in Disease - Extracellular Proteins as Complement Regulators

    Författare :Kaisa Happonen; Malmö Proteinkemi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; joint disease; Complement; proteoglycan; cancer;

    Sammanfattning : Complement activation occurs during inflammatory joint diseases such as rheumatoid arthritis (RA) and is thought to contribute to the chronic inflammation observed within the joints. Previous studies have shown that certain cartilage components of the small leucine-rich repeat protein (SLRP)-family regulate complement activity, thereby possibly contributing to disease progression. LÄS MER

  3. 7. Persistent inflammatory pathways in rheumatoid arthritis despite anti-rheumatic treatment

    Författare :Karina Roxana Gheorghe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The past years have witnessed tremendous progress in the treatment of rheumatoid arthritis, a chronic debilitating autoimmune disease mainly characterized by joint inflammation with progressive tissue destruction and loss of function. This condition affects 0. LÄS MER

  4. 8. Aminoacyl tRNA synthetases and their connection to autoimmune rheumatic disease

    Författare :Charlotta Preger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Idiopathic inflammatory myopathies (IIM, collectively called myositis) are rare autoimmune rheumatic diseases characterized by chronic inflammation and associated with high mortality and morbidity (1, 2). The disease nomenclature tells us that IIM has traditionally been described as a group of diseases mainly affecting the skeletal muscle, with muscle weakness and weakened muscle endurance as the dominating clinical symptoms (3). LÄS MER

  5. 9. Associations Between Rheumatoid Arthritis and Malignant Lymphomas

    Författare :Eva Baecklund; Christer Sundström; Anders Ekbom; Roger Hällgren; Tore Kvien; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; rheumatoid arthritis; malignant lymphoma; diffuse large B-cell lymphoma; disease activity; disease modifying anti-rheumatic drug; Epstein-Barr virus; germinal centre-like non-germinal centre-like subtype; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Patients with rheumatoid arthritis (RA) are at increased risk of developing malignant lymphoma, although details about this association remain unclear. The aims of this thesis were to investigate risk factors for lymphoma in patients with RA and to characterize these lymphomas regarding subtype, presence of Epstein-Barr virus (EBV), clinical manifestations and prognosis. LÄS MER

  7. 10. Signs of inflammation in different types of heart valve disease : The VOCIN study

    Författare :Lars Wallby; Lena Jonasson; Mats Broqvist; Mårten Rosenqvist; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart valve dysfunction; heart valve disease; VOCIN study group; aortic valves; Gross valvular pathology; Cariology; Cariologi;

    Sammanfattning : Heart valve dysfunction is a relatively common condition in the population, whereas significant heart valve disease is more unusual. The cause of different types of heart valve disease depends on which valve is concerned. Rheumatic heart valve disease, has for a long time been considered to constitute a post-inflammatory condition. LÄS MER