Sökning: "inflammatory rheumatic disease"

Visar resultat 21 - 25 av 66 avhandlingar innehållade orden inflammatory rheumatic disease.

  1. 21. On the immunopathogenesis of systemic lupus erythematosus - Immune complexes, type I interferon system, complement system and platelets

    Författare :Christian Lood; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; systemic lupus erythematosus; autoimmunity; rheumatology; immunology; cardiovascular disease;

    Sammanfattning : Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disorder characterized by inflammation in several organ systems. SLE patients have an impaired ability to clear dying cells which leads to the exposure of several nuclear antigens which might break self tolerance. LÄS MER

  3. 22. Chlamydia pneumoniae in Aortic Valve Sclerosis and Thoracic Aortic Disease : Aspects of Pathogenesis and Therapy

    Författare :Christina Nyström-Rosander; Kenneth Persson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Chlamydia pneumoniae; aortic valve sclerosis; trace elements; thoracic aorta; antibiotics; Polymerase Chain Reaction PCR ; electron microscopy EM ; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; infektionssjukdomar; Infectious Diseases;

    Sammanfattning : The obligate intracellular bacterium Chlamydia pneumoniae (Cp), a common human pathogen, has been associated with atherosclerotic cardiovascular disease. The aetiology of non-rheumatic aortic valve sclerosis has, however, not been clarified. LÄS MER

  4. 23. Idiopathic inflammatory myopathies and cancer : familial risk, genetics and consequences

    Författare :Weng Ian Che; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Idiopathic inflammatory myopathies (IIMs) are a group of rare rheumatic inflammatory diseases (RIDs), characterised by a diverse range of clinical, serological and histopathological characteristics, with muscle weakness as a shared hallmark. While advancements in disease management have improved the survival rates of patients with IIM, the mortality rate among patients with IIM is still higher than the general population, mainly due to association with comorbidities such as cancer. LÄS MER

  5. 24. Cardiovascular outcomes and extra-articular manifestations in patients with spondyloarthritis

    Författare :Karin Bengtsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spondyloarthritis; Cardiovascular disease; Extra-articular manifestations;

    Sammanfattning : Background: Spondyloarthritis (SpA) is a cluster of rheumatic diseases with similar clinical features, including association with extra-articular manifestations such as anterior uveitis (AU), inflammatory bowel disease (IBD) and psoriasis. Ankylosing spondylitis (AS), psoriatic arthritis (PsA) and undifferentiated SpA (uSpA) are the major subtypes of SpA. LÄS MER

  7. 25. Reactivity to collagen type II and C1q in rheumatic diseases

    Författare :Johan Rönnelid; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :rheumatoid arthritis; systemic lupus erythematosus; anti-collagen antibodies; anti-Clq antibodies; ELISPOT; interferon-y; IL-4;

    Sammanfattning : In rheumatoid arthritis (RA),other arthritides and in systemic lupus erythematosus (SLE) there is immunological reactivity to collagen type II (CII) and to complement component C1q. Parts of the CII and C1q molecules are structurally and immunologically related. LÄS MER