Sökning: "joint disease"
Visar resultat 1 - 5 av 265 avhandlingar innehållade orden joint disease.
1. Psoriatic arthritis: a complex disease : analyses on genetic and serological biomarkers and of comorbidity
Sammanfattning : Psoriatic Arthritis (PsA) is a heterogonous inflammatory arthritis associated with psoriasis. The disease leads to inflammation of peripheral joints, axial skeleton and/or enthesites, and can result in severe destruction of affected joints. LÄS MER
2. Joint disease biomarkers - discovery and application
Sammanfattning : Dysregulated cartilage homeostasis, articular cartilage degradation and abnormal bone remodeling are common denominators in joint disease and can lead to severe disability for the patients. The molecular pathways behind the disease pathology can overlap across different joint diseases. LÄS MER
3. Complement in Disease - Extracellular Proteins as Complement Regulators
Sammanfattning : Complement activation occurs during inflammatory joint diseases such as rheumatoid arthritis (RA) and is thought to contribute to the chronic inflammation observed within the joints. Previous studies have shown that certain cartilage components of the small leucine-rich repeat protein (SLRP)-family regulate complement activity, thereby possibly contributing to disease progression. LÄS MER
4. Staphylococcal prosthetic joint infections : similar, but still different
Sammanfattning : Staphylococci constitute a major part of our commensal flora but are also the most common bacteria causing prosthetic joint infections (PJIs), a dreaded complication of arthroplasty surgery. However, not all staphylococci are the same. LÄS MER
5. Predictors of disease onset and progression in early rheumatoid arthritis : A clinical, laboratory and radiological study
Sammanfattning : To diagnose rheumatoid arthritis (RA) during the early stages of the disease is often difficult. The disease course shows great inter-individual variation from mild, self-limiting to very severe destruc-tive disease with extra-articular manifestations. LÄS MER