Sökning: "histone post-translational modifications"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden histone post-translational modifications.

  1. 1. Jack of all trades, master of none : the multifaceted nature of H3K36 methylation

    Författare :Henrik Lindehell; Jan Larsson; Anders Byström; Peter B. Becker; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; H3K36; histone methylation; dosage compensation; chromosome-specific gene regulation; transposable elements; PIWI piRNA biosynthesis; Set2; Ash1; NSD; Histone 3.3; post-translational modifications; histone modifications; epigenetics; proximity ligation assay; Drosophila; Genetics; genetik; molekylärbiologi; Molecular Biology; Biopharmaceutics; biofarmaci;

    Sammanfattning : Post-translational modifications of histones enable differential transcriptional control of the genome between cell types and developmental stages, and in response to environmental factors. The methylation of Histone 3 Lysine 36 (H3K36) is one the most complex and well-studied histone modifications and is known to be involved in a wide range of molecular processes. LÄS MER

  3. 2. Regulation of differentiation during the Giardia life cycle : An insight into the molecular control

    Författare :Laura Rojas-López; Staffan Svärd; Marco Lalle; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Giardia; cell differentiation; encystation; histone post-translational modifications; host-parasite interaction;

    Sammanfattning : Giardia intestinalis (syn. G. lamblia, G. duodenalis) is an intestinal protozoan parasite that causes diarrheal infections worldwide. LÄS MER

  4. 3. Chromatin, histones, and epigenetic tags

    Författare :Elisavet Koutzamani; Ingemar Rundquist; Herbert Lindner; Sergey Belikov; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chromatin; histones; histone variants; epigenetics; histone H4 methylation; linker histone phosphorylation; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The fundamental building blocks of chromatin are the nucleosomes. Each such unit is composed of about 200 bp of DNA, the well-conserved core histones (H2A, H2B, H3 and H4) and a linker histone (H1). LÄS MER

  5. 4. Genome-wide patterns of histone modifications in fission yeast

    Författare :Indranil Sinha; Karl Ekwall; Karin Dahlman-Wright; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : DNA is wrapped almost two times around a group of proteins called histones to form a chromosomal structure known as the nucleosome. Both DNA and histones can be modified with different chemical tags by several enzymes to activate or suppress a particular gene or group of genes. Histones can be covalently modified at several places. LÄS MER

  7. 5. Mining DNA elements involved in targeting of chromatin modifiers

    Författare :Philge Philip; Per Stenberg; Jan Larsson; Stein Aerts; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nucleosome; histone; chromatin; chromatin modifiers; targeting; DNA motifs; protein factors; MSL; molekylärbiologi; Molecular Biology;

    Sammanfattning : Background: In all higher organisms, the nuclear DNA is condensed into nucleosomes that consist of DNA wrapped around a core of highly conserved histone proteins. DNA bound to histones and other structural proteins form the chromatin. LÄS MER