Sökning: "Set2"
Hittade 4 avhandlingar innehållade ordet Set2.
1. Jack of all trades, master of none : the multifaceted nature of H3K36 methylation
Sammanfattning : Post-translational modifications of histones enable differential transcriptional control of the genome between cell types and developmental stages, and in response to environmental factors. The methylation of Histone 3 Lysine 36 (H3K36) is one the most complex and well-studied histone modifications and is known to be involved in a wide range of molecular processes. LÄS MER
2. Short and long-term regulation of autophagy
Sammanfattning : Autophagy is a conserved catabolic pathway triggered by stress conditions in which portions of the cytoplasm, damage organelles, misfolded proteins and intracellular bacteria are delivered and degraded in the lysosome/vacuoles. Thus, an efficient induction and completion of the process is required to ensure a proper homeostasis of the cell. LÄS MER
3. Methyltransferase Ash1, histone methylation and their impact on Polycomb repression
Sammanfattning : Antagonistic interactions between Polycomb Group (PcG) and Trithorax Group (TrxG) proteins orchestrate the expression of key developmental genes. Distinct maternally loaded repressors establish the silenced state of these genes in cells where they should not be expressed and later PcG proteins sense whether a target gene is inactive and maintain the repression throughout multiple cell divisions. LÄS MER
4. Platinum(II) and Palladium (II) Complexes with Group 14 and 15 Donor Ligands. Synthesis, Structure and Substitution Mechanisms
Sammanfattning : The present thesis deals with Pd(II) and Pt(II) complexes with group 14 and 15 donor ligands. Such complexes have been prepared and investigated mainly with regard to their ground state structures and the mechanism according to which they undergo substitution. LÄS MER
