Sökning: "heat-shock"

Visar resultat 21 - 25 av 136 avhandlingar innehållade ordet heat-shock.

  1. 21. Hsp70 nucleotide exchange factor Fes1 is essential for protein quality control in Saccharomyces cerevisiae

    Författare :Naveen Kumar Chandappa Gowda; Claes Andréasson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Heat shock protein 70; molecular chaperone; ubiquitin; nucleotide exchange factor; protein quality control; Cell Biology; cellbiologi;

    Sammanfattning : .... LÄS MER

  3. 22. Hand-arm vibration injury - Neurosensory, vascular manifestations, severity grading, and serum biomarkers

    Författare :Eva Tekavec; Arbetsrelaterade besvär i rörelseorganen; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hand-arm vibration injury; Hand-arm vibration syndrome HAVS ; Raynaud s phenomenon; Nerve injury; Seum biomarkers; Vibration perception thresholds; Griffin scores; Stockholm work shop scale; International consensus criteria; Calcitonin gene related peptide; Thrombomodulin; Heat shock protein 27; Caspase 3; ICAM-1; MCP-1; von Willebrand factor; cold intolerance; Small fibre neuropathy; Hand-arm vibrations skada; Nerv skada; Köldintolerans;

    Sammanfattning : .... LÄS MER

  4. 23. The conserved methionines in the chloroplast small heat shock protein - Role in chaperone-substrate interactions and effects of methionine sulfoxidation on chaperone activity

    Författare :Niklas Gustavsson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biochemistry; oxidative stress; thermostability; temperature stress; stress tolerance; sHsp; protein aggregation; molecular chaperone; Heat stress; methionine sulfoxidation; Biokemi; metabolism; Plant biochemistry; Växtbiokemi;

    Sammanfattning : The chloroplast-localized small heat shock protein (sHsp) Hsp21 belongs to the family of alpha-crystallin like sHsps which form large oligomeric structures and protect partly unfolded aggregation-prone proteins against aggregation. The main focus for this thesis has been on the highly conserved methionines in Hsp21. LÄS MER

  5. 24. A Chloroplast Localized Small Heat Shock Protein, Hsp21. Importance of Hsp21 in stress protection of transgenic Arabidopsis thaliana, recombinant expression and characterization of oxidation-dependent conformational changes

    Författare :Ulrika Härndahl; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; a-crystallin; sHsp; chaperone; amphipathic a-helix; oligomer; redox-regulated; methionine sulfoxidation; oxidative stress; regulation; protein structure; circular dichroism; mass spectrometry; fluorescence spectroscopy; Biochemistry; Metabolism; Biokemi;

    Sammanfattning : A specific group of heat shock proteins, the so called small heat shock proteins (sHsps), exists in all organisms but are especially abundant in plants. The sHsps prevent aggregation of other proteins (substrate proteins) during transient heat and oxidative stress. LÄS MER

  7. 25. Studies of myc gene expression and a novel endoribonuclease activity

    Författare :Anders Wennborg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :c-myc; B-myc; heat-shock; mRNA degradation; endoribonucleases; AUUUAmotifs; RNase E.;

    Sammanfattning : The general aim of this work was to study the regulation of cellular oncogene expression, with emphasis on the c-myc gene, which is de-regulated in several human and animal tumors. The steady-state expression level of c-myc mRNA or protein was analyzed in panels of human Blymphoid cell lines with different growth and transformation properties, and the general observation was a co-variation between high c-myc expression and a more malignant phenotype of the cell lines. LÄS MER