Sökning: "Caspase 3"
Visar resultat 1 - 5 av 185 avhandlingar innehållade orden Caspase 3.
1. Caspase-3 in lens epithelium
Sammanfattning : Purpose: To model the time evolution of active caspase-3 protein expression in a healthy lens, and in a lens exposed to UVR-300 nm (UVR-B). To develop an automated method to classify the fluorescent signal of biomarkers in the lens epithelial cells.Methods: Six-week old Sprague-Dawley rats were used. LÄS MER
2. Inflammatory Reactions in Peritonitis and Malignant Obstructive Jaundice : Clinical and Experimental Studies with Special Emphasis on the Cellular Immune Response
Sammanfattning : Patients with peritonitis or malignant obstructive jaundice (HPB+) have an increased morbidity and mortality due to sepsis. An altered cell-mediated immunity in the intestinal mucosa might promote gut barrier failure, increased endotoxin and cytokine release and bacterial translocation (BT) in these conditions. LÄS MER
3. Genetic studies of neuroblastoma with emphasis on the apoptotic pathway
Sammanfattning : Aim: The objective of this thesis was to find genes and chromosomal regions involved in neuroblastoma (NB) tumor progression. NB is a childhood tumor of the sympathetic nervous system that generally occurs spontaneously. LÄS MER
4. Caspase-dependent and caspase-independent neuronal injury in the developing brain
Sammanfattning : Aims: To investigate the mechanisms of neuronal cell death after hypoxia-ischemia in the developing brain.Methods: Rats or mice were subjected to left common carotid artery ligation plus hypoxia. Animals were sacrificed at certain time points after hypoxia-ischemia. LÄS MER
5. Caspase activation in human neuroblastoma cells: mechanisms and spatiotemporal aspects
Sammanfattning : Apoptosis is one of the modes of programmed cell death, in which several members of the caspase family of proteases play the central role. However, activation of apoptotic caspases does not necessarily lead to cell death. LÄS MER