Sökning: "gene expression"

Visar resultat 6 - 10 av 3628 avhandlingar innehållade orden gene expression.

1. 6. Gene Expression in Cancer Cells : Detection of Splice Variants, Allele-specific Expression and DNA Methylation

   Författare :Lili Milani; Ann-Christine Syvänen; Thomas R. Gingeras; Uppsala universitet; []
   Nyckelord :;

   Sammanfattning : The human genome sequencing project has provided a wealth of information on sequence variation between individuals. The surprisingly low number of genes in the human genome is compensated for by a complex regulation of gene expression. LÄS MER

3. 7. Gene and protein expression in denervated atrophic and hypertrophic skeletal muscle

   Författare :Marlene Norrby; Sven Tågerud; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Skeletal muscle; Denervation; Hypertrophy; Atrophy; Gene expression; Protein expression; Protein phosphorylation; NIFK; Wnt; MK2; Akt signaling;

   Sammanfattning : Following denervation skeletal muscles change their functional and structural properties. Some changes resemble conditions in developing muscles and may be important for reinnervation. Due to inactivity following denervation most skeletal muscles loose muscle mass and become atrophic. LÄS MER

4. 8. Nonlinear dimensionality reduction of gene expression data

   Författare :Jens Nilsson; Matematik LTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Gene expression; Manifold learning; Nonlinear dimensionality reduction; Microarray;

   Sammanfattning : Using microarray measurements techniques, it is possible to measure the activity of genes simultaneously across the whole genome. Since genes influence each others activity levels through complex regulatory networks, such gene expression measurements are state samples of a dynamical system. LÄS MER

5. 9. Organization of mitochondrial gene expression in yeast : Specific features of organellar protein synthesis

   Författare :Kirsten Kehrein; Martin Ott; Thomas A Fox; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; translation; bc1 complex; ribosome; gene expression; Biochemistry; biokemi;

   Sammanfattning : Mitochondria contain their own genetic system, encoding key subunits of the oxidative phosphorylation system. These subunits are expressed by an organelle-specific gene expression machinery. LÄS MER

7. 10. Deconvolution of Spatial Gene Expression in Cancer

   Författare :Linnea Stenbeck; Stefania Giacomello; Joakim Lundeberg; Vicent Pelechano; KTH; []
   Nyckelord :Spatial transcriptomics; Gene expression; Cancer; Bioteknologi; Biotechnology;

   Sammanfattning : Cancer is the second leading cause of death in the world, claiming nearly 10 million lives in 2020 alone. One of the main issues in anti-cancer treatment is the heterogeneity of the tumor microenvironment (TME). The TME consists of different cells that are critical for cancer development. LÄS MER