Sökning: "gene expression"

Visar resultat 11 - 15 av 3624 avhandlingar innehållade orden gene expression.

  1. 11. Gene Expression and DNA Methylation in Acute Lymphoblastic Leukemia

    Författare :Jessica Nordlund; Syvänen Ann-Christine; Xavier Estivill; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Digital gene expression; Allele-specific gene expression; DNA methylation; Epigenetics; Acute lymphoblastic leukemia; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Pediatric acute lymphoblastic leukemia (ALL) is the most common malignancy in children, which results from the malignant transformation of progenitor cells in the bone marrow into leukemic cells. The precise mechanisms for this transformation are not well defined, however recent studies suggest that aberrant regulation of gene expression or DNA methylation may play an important role. LÄS MER

  3. 12. Adipose tissue gene expression & candidate genes for obesity

    Författare :Lovisa Johansson; Diabetes - klinisk obesitasforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Insulin resistance; Obesity; Adipose tissue; Adiponutrin; PNPLA; PPARGC1A; Gene expression; Case-control association study; Microarray; Genotyping; Population-based study;

    Sammanfattning : Obesity results from an interaction between genetic and environmental factors and is a growing health problem associated with development of insulin resistance, type 2 diabetes and cardiovascular disease. This thesis has focused on investigating the genetic contribution in obesity and insulin resistance by both candidate and global gene approaches with focus on the adipose tissue. LÄS MER

  4. 13. Regulation of chloroplast gene expression in higher plants

    Författare :Anna Furo Tullberg; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein tyrosine kinase; plastoquinone pool; redox; Pisum sativum; Sinapis alba; petB; psaB; chloroplast; gene expression; Physiological biophysics; Växtfysiologi; light harvesting complex II;

    Sammanfattning : Chloroplast gene expression is regulated by developmental and environmental signals. It has been proposed that there is a direct coupling between electron transport in biological membranes and gene expression (J. F. Allen, 1992, Biochim. LÄS MER

  5. 14. Sexual Conflict and Gene Expression in Drosophila melanogaster

    Författare :Paolo Innocenti; Edward Morrow; Göran Arnqvist; Andrew G Clark; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sexual conflict; sexual selection; male-female coevolution; gene expression; transcriptome; microarrays; sexual dimorphism; Drosophila; Biology; Biologi; Biologi med inriktning mot zooekologi; Biology with specialization in Animal Ecology; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Sexual conflict is broadly defined as a conflict between the evolutionary interests of the two sexes. Depending on the genetic architecture of the traits involved, it can occur at the level of male-female interactions or take the form of selection acting to change the mean of a shared trait against the sign of its genetic correlation. LÄS MER

  7. 15. Preproenkephalin Gene and mRNA : Studies of Structure, Function, Cocaine Responses in an Animal Model, and Genetic Association with Human Opiate Addiction

    Författare :Karl Steven LaForge; Fred Nyberg; Peter S. Eriksson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biological research on drug dependence; Neuropeptides; Endogenous opioid system; Drug addiction; Heroin; Cocaine; Gene expression; Genetic association; Biologisk beroendeforskning; Biological research on drug dependence; Biologisk beroendeforskning;

    Sammanfattning : The endogenous opioid enkephalin neuropeptides are mediators of pain perception and have been implicated in human addictions. The preproenkephalin gene and its mRNA have also provided many examples of tissue- and species-specific variations in mRNA structure produced through a variety of transcriptional and post-transcriptional mechanisms. LÄS MER