Sökning: "founder"

Visar resultat 6 - 10 av 130 avhandlingar innehållade ordet founder.

  1. 6. Genetic and Molecular analysis of the Spinocerebellar ataxia type 7 (SCA7) disease gene

    Författare :Jenni Jonasson; Monica Holmberg; Christine Van Broeckhoven; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spinocerebellar ataxia; human genetics; linkage analysis; anticipation; CAG repeat expansion; founder effect; protein expression; ATXN7; Medical genetics; Medicinsk genetik;

    Sammanfattning : Spinocerebellar ataxia type 7 (SCA7) is a hereditary neurodegenerative disorder affecting the cerebellum, pons and retina. SCA7 patients present with gait ataxia and visual impairment as the main symptoms. LÄS MER

  3. 7. Predicting who stays or leaves after the acquisition: : Target’s top manager turnover

    Författare :Keivan Aghasi; Terrence Brown; Massimo Colombo; Maureen McKelvey; KTH; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Acquisition; CEO turnover; TMT turnover; coordination; Founder-CEO; Similarity attraction; Diversity;

    Sammanfattning : In acquisition of high-tech and knowledge intensive firms, scholars have paid special attention to top managers’ status after the deal. Literature suggests that these managers in particular CEOs if kept in post-acquisition provide coordination capacity for the acquirer to transfer the knowledge and technology from the target to the acquirer while minimizing the disruptive effect of post-acquisition integration process. LÄS MER

  4. 8. Hereditary transthyretin amyloidosis (ATTR V30M) : from genes to genealogy

    Författare :Nina Norgren; Ole Suhr; Alda Sousa; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hereditary transthyretin amyloidosis; Familial amyloid polyneuropathy; transthyretin; genealogy; founder effect; miRNA; allele-specific expression; gene expression; liver; medicin; Medicine;

    Sammanfattning : Background: Hereditary transthyretin amyloidosis is an autosomal dominant disease with a reduced penetrance. The most common mutation in Sweden is the V30M mutation in the transthyretin gene. Clustering areas of the disease can be found in Northern Sweden, Portugal, Brazil and Japan, although sporadic cases exist worldwide. LÄS MER

  5. 9. Who am I, and if so, how many? Identity dynamics in agricultural entrepreneurship

    Författare :Sarah Fitz-Koch; Mattias Nordqvist; Jönköping University; Sveriges lantbruksuniversitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; identity dynamics; multiple work identities; entrepreneurship; new venture; agriculture; family business; entrepreneurial identity; founder identity;

    Sammanfattning : Identity matters and identity is hailed increasingly as central to fully apprehending entrepreneurship. Identity is inherent to entrepreneurship because entrepreneurs establish and grow their ventures based on their identities. Hence, identity infuses entrepreneurial activities with meaning and guidance. LÄS MER

  7. 10. Dispersal, inbreeding and fitness in natural populations

    Författare :Bengt Hansson; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; immigration; inbreeding; inbreeding depression; heterozygosity; microsatellite; great reed warbler; bird; Djurekologi; Animal ecology; philopatry; heritability; founder event; dispersal; bottleneck;

    Sammanfattning : To evaluate how inbreeding affects the viability of small populations, it is crucial to determine what constitutes a population (i.e., the number of breeders in local patches and the degree of dispersal), and also to estimate the reproductive consequences of philopatry and emigration. LÄS MER