Sökning: "fluid age"

Visar resultat 11 - 15 av 203 avhandlingar innehållade orden fluid age.

1. 11. Clinical and Pharmacological Aspects of Selective Serotonin Reuptake Inhibitors in the Treatment of Depression in Old Age

   Författare :Jöns Lundmark; Finn Bengtsson; Leif Lindström; Linköpings universitet; []
   Nyckelord :Serum concentrations; cerebrospinal fluid; pharmacokinetics; selective serotonin reuptake inhibitors; therapeutic drug monitoring; elderly; depression; pharmaceutical economics; MEDICINE; MEDICIN;

   Sammanfattning : Objective: The aim of the present thesis is to examine the pharmacokinetic and biochemical effects of the selective serotonin reuptake inhibitors (SSRIs) in the elderly.Background: Symptoms of depression are found in up to 15% of the elderly and the prevalence of major depression is reported to be about 3%. LÄS MER

3. 12. The Cerebrospinal Fluid in Severe Pain Conditions : Clinical, Pharmacological and Proteomic Aspects

   Författare :Emmanuel Bäckryd; Björn Gerdle; Jan Sörensen; Britt Larsson; Bijar Ghafouri; Mads Werner; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The treatment of both cancer pain and non-cancer chronic pain is still suboptimal. The overall aim of this PhD thesis was to conduct translational pain research at the interface between clinical pain medicine and the field of human proteomics, using the practice of intrathecal analgesia at our institution as a starting point. LÄS MER

4. 13. Mathematical modelling of clinical applications in fluid therapy

   Författare :Peter M Rodhe; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: This thesis presents a new application of fluid kinetic analysis using mathematical tools to evaluate fluid therapy problems. Several models were developed to mathematically handle fluid distribution concerning bleeding and anaesthesia, arterio-venous differences in plasma dilution, peripheral fluid accumulation and differences in fluid distribution among young and elderly patients. LÄS MER

5. 14. Closer Together or Further Apart? : Public administration and archives in the digital age

   Författare :Ann-Sofie Klareld; Erik A. M. Borglund; Karen Anderson; Julie McLeod; Mittuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; archives; digital work processes; discourse; outsourcing; public sector agencies; recordkeeping; records continuum model; Sweden;

   Sammanfattning : The research presented in this thesis is about recordkeeping in the public sector, focusing especially on the relationship between the public administration and its archives, and selected aspects affecting the way this relationship is developing in the digital era. Two research questions are addressed: RQ1: What are ‘archives’ and ‘recordkeeping’ in the digital context and the developing e-government? RQ2: What are the indications of current and future challenges regarding the cooperation between public administration and archives? Six studies resulting in six papers form the basis of the thesis. LÄS MER

7. 15. Aspects of hepatoduodenal trauma and fluid therapy in hemorrhagic shock

   Författare :Peep Talving; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Liver injury; epidemiology; population-based study; duodenum injury; gunshot injury; surgery; trauma; emergency care; bleeding; hypotension; hemorrhagic shock; fluid resuscitation; prehospital fluid therapy; morbidity; mortality;

   Sammanfattning : Traumatic injury is the leading cause of death among young adults and children, accounting for 5 million deaths worldwide on an annual basis. In Sweden alone, 2500 individuals succumb to traumatic injuries yearly. Beyond the burden of death, injuries contribute to a large proportion of disability. LÄS MER