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Visar resultat 21 - 25 av 107 avhandlingar som matchar ovanstående sökkriterier.

1. 21. Hormonal Regulation of the Human CYP27A1 and CYP7B1 Genes

   Författare :Wanjin Tang; Kjell Wikvall; Maria Norlin; Mats Gåfvels; Uppsala universitet; []
   Nyckelord :Pharmaceutical biochemistry; CYP27A1; CYP7B1; cholesterol; estrogen; androgen; prostate; glucocorticoid receptor; fetal development; Farmaceutisk biokemi;

   Sammanfattning : CYP27A1 and CYP7B1 are widely expressed in various human tissues and are two key enzymes involved in the pathways for conversion of cholesterol to bile acids. Also, CYP27A1 is involved in bioactivation of vitamin D3 and CYP7B1 plays a role in 7alpha-hydroxylation of dehydroepiandrosterone and other steroids. LÄS MER

3. 22. The role of estrogen receptors in the auditory system

   Författare :Konstantina Charitidi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Both laboratory and clinical studies have previously demonstrated estrogenic effects on auditory function. The overall scope of this study was to investigate the physiological and molecular involvement of estrogens and estrogen receptors alpha (ERα) and beta (ERβ) in hearing physiology. LÄS MER

4. 23. Occurrence and ecotoxicity of endocrine disruptor chemicals in aquatic environment and sewage treatment systems

   Författare :Andre Luis de Sa Salomao; Marcia Marques; Paulo Sergio Martins Carvalho; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Endocrine disruption; Alkali-labile phosphate; Estrogen hormones; Oreochromis niloticus; Unicellular green microalgae; Additive effect; Less-than additive effect; Chronic toxicity; Natural Science; Naturvetenskap;

   Sammanfattning : The applicability of one selected method for indirect measurement of vitellogenin (Vtg) in fish plasma based on the quantification of alkali-labile phosphates (ALP method) to assess estrogenicity in water was investigated. The ALP method applied in this investigation was originally developed with Carassius carassius (Crucian carps). LÄS MER

5. 24. Sex steroid effects on normal breast tissue

   Författare :Gunnar Söderqvist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Estrogen receptor; progesterone receptor; proliferation; breast epithelialcells; mammary epithelium; sulfatase; 17 HSD; regional differences; sex steroids;

   Sammanfattning : In Sweden, it is estimated that about one million women are treated with estrogen/progestogen for contraception and hormone replacement therapy (HRT). The possibility of an increased cancer risk in target organs has been vividly discussed for many years. LÄS MER

7. 25. Estrogen receptor expression in relation to pain modulation and transmission : experimental studies in rats

   Författare :Åsa Amandusson; Anders Blomqvist; Kaj Fried; Ola Hermanson; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical cell biology; Medicinsk cellbiologi; Medical Cell Biology; Medicinsk cellbiologi; MEDICINE;

   Sammanfattning : Estrogens have a remarkably wide range of actions in the mammalian brain. They not only play a pivotal role in reproductive behavior and sexual differentiation, but also contribute to e.g. thermoregulation, feeding, memory, neuronal survival and the perception of somatosensory stimuli. LÄS MER