Sökning: "sulfatase"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet sulfatase.
1. Strategies to improve and balance the expression levels of recombinant proteins in mammalian cell lines
Sammanfattning : Proteins are the building blocks of all living organisms enabling us to function and survive. There are more than 100,000 different proteins in the human body performing a variety of vital tasks. LÄS MER
2. Molecular investigation of mucopolysaccharidosis type II (Hunter syndrome) in man
Sammanfattning : Mucopolysaccharidosis type II or Hunter syndrome is a rare lysosomal storage disorder caused by a deficiency in the enzyme iduronate-2-sulfatase (IDS). The disorder is inherited in an X-linked recessive fashion and has a broad spectrum of clinical phenotypes ranging from severe to mild. LÄS MER
3. Development of chemical biology tools for metabolomics analysis : Phase II modifications as a link between host and microbiota co-metabolism
Sammanfattning : Biomarker discovery is an extremely important field for early disease detection. New selective molecular markers are in high demand, as an earlier disease detection can lead to improved patient care. LÄS MER
4. Sex steroid effects on normal breast tissue
Sammanfattning : In Sweden, it is estimated that about one million women are treated with estrogen/progestogen for contraception and hormone replacement therapy (HRT). The possibility of an increased cancer risk in target organs has been vividly discussed for many years. LÄS MER
5. Studies of carbohydrate structure, properties and interactions by nmr spectroscopy
Sammanfattning : In this thesis the structure, properties and interactions of different types of carbohydrates were investigated by NMR spectroscopy. The structures of kappa- (κ) and kappa/mu- (κ/μ) carrageenan oligosaccharides were analyzed by studying the hydroxy protons. LÄS MER