Sökning: "mammary epithelium"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden mammary epithelium.
1. Histologic characterization of stem cells in mammary epithelium and stroma
Sammanfattning : It is unknown whether native cells in benign breast tissue mediate risk of cancer.We therefore aimed to identify cell types in benign human mammary tissueimmunohistologically using markers of stemness and differentiation, and toinvestigate their possible associations with clinical risk factors for breast cancer. LÄS MER
2. Hypoxia and Hypoxia-Inducible Factors in Normal and Malignant Breast Epithelium
Sammanfattning : Breast cancer treatment is based on tumor and patient related factors such as tumor stage, grade, hormonal status, HER2 status, patient age, and family history to name a few. It is today widely acknowledged that hypoxia and hypoxia-inducible factors (HIF:s) contribute to tumor progression. LÄS MER
3. Transport proteins in mammary epithelial cells : studies in murine (HC11) and bovine (BME-UV) cells - effects of prochloraz
Sammanfattning : Transporters localized in membranes of secreting mammary epithelial cells are involved in delivery of essential nutrients into milk. However, drugs and other xenobiotics may be substrates of these transporters and thus be actively secreted into milk, which may pose a health threat to breastfed infants and dairy consumers. LÄS MER
4. Sex steroid effects on normal breast tissue
Sammanfattning : In Sweden, it is estimated that about one million women are treated with estrogen/progestogen for contraception and hormone replacement therapy (HRT). The possibility of an increased cancer risk in target organs has been vividly discussed for many years. LÄS MER
5. PAK4 signaling in development and cancer
Sammanfattning : Our understanding of cancer biology has been evolving rapidly shaped by groundbreaking discoveries. We now understand that cancer is not one disease but many, and that tumors are not foreign objects in the human body but rather the result of changes in the previously normal tissues and organs. LÄS MER