Sökning: "drug therapy"

Visar resultat 6 - 10 av 673 avhandlingar innehållade orden drug therapy.

  1. 6. Drug therapy - a challenge in primary care

    Författare :Veronica Milos; Allmänmedicin och samhällsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug therapy; elderly; guidelines; primary care; potentially inappropriate medications; fall risk increasing drugs; antibiotics; upper respiratory tract infections; attitudes; adherence; general practitioners; Sweden;

    Sammanfattning : Introduction: Drug therapy in primary care is a broad field, with two areas previously identified as particularly challenging: treatment of the elderly and prescription of antibiotics against uncomplicated upper respiratory tract infections (URTIs). General practitioners’ (GPs’) attitudes and adherence to evidence-based treatment guidelines might be influenced by different interventions and need to be studied. LÄS MER

  3. 7. Pericyte Influence on Drug Delivery Across the Blood-Brain Barrier : Implications for Therapy of Neurodegenerative Diseases

    Författare :Nebojsa Mihajlica; Margareta Hammarlund-Udenaes; Christer Betsholtz; William Elmquist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; pericytes; pericyte-deficiency; pharmacokinetics; small-molecular drugs; drug distribution; transporters; P-glycoprotein; tyrosine kinase inhibitors; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy;

    Sammanfattning : The blood-brain barrier (BBB) represents a complex interface between the brain parenchyma and systemic blood circulation, strictly controlling exchange of substances between the two sites. Pericytes are mural cells located on the abluminal membrane of the brain endothelium, involved in BBB formation and maintenance. LÄS MER

  4. 8. Optimizing drug therapy among people with dementia : the role of clinical pharmacists

    Författare :Maria Gustafsson; Hugo Lövheim; Maria Sjölander; Jörn Schneede; Stig Karlsson; Håkan Melhus; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychotropic drugs; potentially inappropriate drugs; drug-related problems; old people; dementia; nursing homes; drug-related hospitalizations; medication reviews; clinical pharmacists; geriatrik; Geriatrics;

    Sammanfattning : Background: Drugs are one of the cornerstones in the management of many diseases. In general, drugs are used for diagnosis, prevention, mitigation of symptoms, and, sometimes, to cure disease. However, drug treatment in elderly people, especially those with dementia and cognitive impairments, may involve significant risk of adverse drug events. LÄS MER

  5. 9. TA i missbruksarbete : Transaktionsanalytisk psykoterapi som behandlingsmetod för drogmissbrukare i miljöterapeutisk vård

    Författare :Thomas Ohlsson; Institutionen för psykologi; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Psychology; Punkten; Kolleberga; Korsaröd; Vallmotorp; Tomkins; Berne; affects; human being theory; mileau therapy; group therapy; psychotherapy; TC; Therapeutic Communities; TA; Transactional Analysis; Drug abuse; addiction; Social medicine; Sociology; Punkten; Kolleberga; Korsaröd; Vallmotorp; Tomkins; Berne; TA; Psykologi; Socialmedicin; samhällsmedicin; Sociologi;

    Sammanfattning : This monograph studies the outcomes of transactional analysis (TA) psychotherapy with addicts of heavy drugs in long time residential treatment (one year or more) at Swedish therapeutic communities (TCs) during the 1990s. Two sets of data were obtained: The primary material concerned results of approximately one year of TA-therapy; the secondary specific TA-therapy results versus total mileau therapy results. LÄS MER

  7. 10. Modeling of combination therapy to support drug discovery in oncology

    Författare :Tim Cardilin; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Pharmacokinetics Pharmacodynamics; Oncology; Nonlinear Mixed-Effects Models; Model-Based Drug Development; Combination Therapy;

    Sammanfattning : Mathematical models based on ordinary differential equations, with impulses, are used to describe tumor growth after different treatment combinations, including chemicals as well as radiation. The models are calibrated, using a nonlinear mixed-effects framework, based on time series data of tumor volume from animal experiments. LÄS MER