Sökning: "developmental neurotoxicology"

Hittade 2 avhandlingar innehållade orden developmental neurotoxicology.

  1. 1. Neurodevelopmental Consequences of Exposure to Paracetamol (Acetaminophen) and Related Drugs : Experimental studies in mice

    Författare :Gaëtan Philippot; Robert Fredriksson; Vesna Jevtovic-Todorovic; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; paracetamol acetaminophen ; developmental neurotoxicology; delta9-tetrahydrocannabinol THC ; ibuprofen; endocannabinoid system; neonatal mice; brain growth spurt; behavior; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

    Sammanfattning : Paracetamol (acetaminophen) is the analgesic pharmaceutical most commonly used during pregnancy and early life. While therapeutic doses of paracetamol are considered harmless during these periods, recent findings in both humans and rodents suggest a link between developmental exposure to paracetamol and behavioral consequences later in life. LÄS MER

  3. 2. Proteomic Characterization of Induced Developmental Neurotoxicity

    Författare :Henrik Alm; Lennart Dencker; R Stuart Cobb; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; Brain Development; Neurotoxicity; 2D-DIGE; Brain Growth Spurt; Polybrominated Diphenyl Ether; Neonatal; Striatum; Hippocampus; Cerebral Cortex; Parkinsonism; Dyskinesia; Toxicology; Toxikologi; Toxicology; Toxikologi;

    Sammanfattning : The developing brain goes through a number of developmental periods during which it displays an increased sensitivity to exogenous disturbances. On such period is the so called “Brain growth spurt” (BGS) which in humans takes place starting from the third trimester of pregnancy and throughout the first few years of life. LÄS MER