Sökning: "cytoreductive surgery"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden cytoreductive surgery.

  1. 1. Loco-regional Treatment of Peritoneal Carcinomatosis: Survival, Morbidity and Quality of Life

    Författare :Johan Hansson; Haile Mahteme; Wilhelm Graf; Peter Nygren; Peter Naredi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peritoneal carcinomatosis; Cytoreductive surgery; Intraperitoneal chemotherapy; Survival; SPECT; Morbidity; Mortality; Quality of life; Surgery; Kirurgi; Oncology; onkologi;

    Sammanfattning : Peritoneal carcinomatosis (PC) is traditionally regarded as a terminal stage of disease with a poor prognosis and systemic chemotherapy is regarded as palliative treatment. In order to improve survival and even to achieve cure for selected patients with PC, cytoreductive surgery and intraperitoneal che-motherapy have been advocated. LÄS MER

  3. 2. Clinical and Experimental Studies in Peritoneal Metastases from Gastric Cancer

    Författare :Bo Hultman; Haile Mahteme; Bruno Walther; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastric cancer; peritoneal metastases; peritoneal carcinomatosis; epidemiology; prognostic factor; survival; neoadjuvant chemotherapy; cytoreductive surgery; HIPEC; health economy; costs; systemic chemotherapy; cultured tumor cells; fluorometric analysis; cancer drug tests; chemo-sensitivity; anti tumor drugs.; Surgery; Kirurgi;

    Sammanfattning : Gastric cancer (GC) is one of leading causes of death in the world, and peritoneal metastases (PM) are a major site of recurrence. PM from GC implies a poor prognosis, with median overall survival (mOS) approximately 3 months and no survival at five years. LÄS MER

  4. 3. A Pharmacokinetic and Pharmacodynamic Rationale for Perioperative Cancer Chemotherapy in Patients with Peritoneal Carcinomatosis

    Författare :Kurt Van der Speeten; Haile Matheme; Paul Sugarbaker; Lars Pahlman; Ingvar Syk; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peritoneal carcinomatosis; Cytoreductive surgery; Intraperitoneal Chemotherapy; HIPEC; EPIC; Pharmacokinetics; Pharmacodynamics; Morbidity; Mortality; Surgery; Kirurgi; Kirurgi; Surgery;

    Sammanfattning : Peritoneal carcinomatosis (PC) is a common manifestation of both gastrointestinal and gynecologic malignancies. Until recently, this condition was considered beyond curative intent treatment. Since the 1980s, new treatment strategies combining cytoreductive surgery (CRS) with perioperative intraperitoneal and intravenous chemotherapy have emerged. LÄS MER

  5. 4. Cytoreductive Surgery and Intraperitoneal Chemotherapy in Patients with Peritoneal Metastases from Colorectal Cancer : Aspects of loco-regional treatment outcome, patient selection, and chemo-sensitivity

    Författare :Peter H Cashin; Haile Mahteme; Wilhelm Graf; Peter Nygren; Frans Zoetmulder; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kirurgi; Surgery; Oncology; Onkologi;

    Sammanfattning : Previously, peritoneal metastases(PM) from colorectal cancer(CRC) have been considered a terminal and generalised form of cancer. A new treatment strategy combining cytoreductive surgery(CRS) and intraperitoneal chemotherapy(IPC) has recently shown promising results. LÄS MER

  7. 5. Pseudomyxoma Peritonei : Aspects of Natural History, Learning Curve, Treatment Outcome and Prognostic Factors

    Författare :Håkan Andréasson; Haile Mahteme; Lars Påhlman; Brendan Moran; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseudomyxoma peritonei; Natural history; Learning curve; Cytoreductive surgery; Debulking surgery; Treatment outcome; Prognostic factors; PINCH;

    Sammanfattning : Pseudomyxoma peritonei (PMP) is a rare disease characterized by mucinous peritoneal metastasis (PM). Different loco-regional treatment strategies, i.e. debulking surgery and cytoreductive surgery (CRS) in combination with hyperthermic intraperitoneal chemotherapy (HIPEC), have changed the prognosis for these patients. LÄS MER