Sökning: "cancer drug tests"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden cancer drug tests.

  1. 1. Drug repositioning in chemoprevention of colorectal cancer

    Författare :Naiqi Zhang; Allmänmedicin och klinisk epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug repositioning; Colorectal cancer CRC ; Pharmacoepidemiology; Chemoprevention; Melatonin; Proguanil; Atovaquone; Selective serotonin reuptake inhibitor SSRI ;

    Sammanfattning : BackgroundColorectal cancer (CRC) ranks as the third most frequently occurring cancer and the second leading cause of cancer-related deaths worldwide. In response to the high demand for an effective prevention strategy, chemoprevention, using medications to block the pathogenetic pathways of disease, might be an attractive strategy to offer a more effective option at a low cost. LÄS MER

  3. 2. Aspects of Endocrine Therapy in Primary Breast Cancer. Risk Profiling and Adherence Perspectives for Improving Tailored Adjuvant Treatment

    Författare :Christine Lundgren; LUCC: Lunds universitets cancercentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Abstract: Breast cancers are heterogeneous tumours. Prognostic markers are needed to better profile the patient´s risk, and predictive markers to indicate the expected benefit of systemic treatment. Using gene expression analyses, breast tumours can be divided into intrinsic subtypes. LÄS MER

  4. 3. Clinical and Experimental Studies in Peritoneal Metastases from Gastric Cancer

    Författare :Bo Hultman; Haile Mahteme; Bruno Walther; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastric cancer; peritoneal metastases; peritoneal carcinomatosis; epidemiology; prognostic factor; survival; neoadjuvant chemotherapy; cytoreductive surgery; HIPEC; health economy; costs; systemic chemotherapy; cultured tumor cells; fluorometric analysis; cancer drug tests; chemo-sensitivity; anti tumor drugs.; Surgery; Kirurgi;

    Sammanfattning : Gastric cancer (GC) is one of leading causes of death in the world, and peritoneal metastases (PM) are a major site of recurrence. PM from GC implies a poor prognosis, with median overall survival (mOS) approximately 3 months and no survival at five years. LÄS MER

  5. 4. Computer-aided drug design approaches in developing anti-cancer inhibitors

    Författare :Chunxia Gao; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry;

    Sammanfattning : The thesis entitled “computer-aided drug design approaches in developing anti-cancer drug” is divided into a total of six chapters. In the first chapter, an overview of drug discovery and development are introduced. LÄS MER

  7. 5. Prostate cancer : investigating diagnosis, treatment and outcomes

    Författare :Axel Möller; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Prostate cancer is difficult to study. The prostate is located so that it is hard to palpate and because of the dense pelvic bones it is hard to visualize using radiology such as computed tomography. The prostate increases in size with age and it can be irregular in shape and consistency without the presence of cancer. LÄS MER