Sökning: "coreceptor"

Visar resultat 16 - 20 av 35 avhandlingar innehållade ordet coreceptor.

  1. 16. Infections with HIV-1 and mycobacterium tuberculosis : the role of HLA class II alleles and HIV phenotypes

    Författare :Simani Gaseitsiwe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human Immunodeficiency Virus (HIV) and Mycobacterium tuberculosis (M.tb), are the two infectious diseases causing the greatest number of deaths globally. The burden of these infections is most felt in the developing world particularly in sub-Saharan Africa. This is also a region where some of the studies in this thesis were conducted. LÄS MER

  3. 17. HIV-1 variability in relation to host defence mechanisms and disease outcome

    Författare :Marianne Jansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; peptides; seroreactivity; genetic variability; pediatric; disease outcome; biological phenotypes; B-chemokines; coreceptors; V3; V2.;

    Sammanfattning : Genetic variability is a major characteristic of HIV-1. Virus variants evolve rapidly, not only globally, but also within single individuals as a result of an error-prone reverse transcriptase, a rapid virus population turnover and selective pressure from the host. LÄS MER

  4. 18. Intrahost evolution of HIV-1 phenotypes

    Författare :Marie Borggren; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : HIV-1 evolves constantly within an infected individual, due to its mutation-prone viral enzyme, high viral turnover and pressure from the host immune system. Therefore, viruses isolated at different time points from the same individual are never exactly the same and, accordingly, rarely function the same way. LÄS MER

  5. 19. A molecular network mediating adventitious root initiation in Arabidopsis thaliana

    Författare :Abdellah Lakehal; Catherine Bellini; Malcolm Bennett; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Adventitious rooting; auxin; jasmonate; cytokinin; phytohormone perception and signalling; vegetative propagation;

    Sammanfattning : To adapt to the ever-changing rhizosphere conditions, land plants evolved a sophisticated root system. The genetic determinants of the root system establishment have been the targets of natural selection, resulting in a very complex but robust molecular networks and circuits. LÄS MER

  7. 20. The central role of the CD4 T-helper cell in HIV infection : analysis of cell mediated responses and CCR-5 genotypes in HIV-1 infected individuals

    Författare :Ann-Charlotte Leandersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human immunodeficiency virus (HIV) infection is characterized by progressive immunologic dysregulation. The main target of HIV is the CD4 cell resulting in malfunction of the immune system, with a decline in CD4 cells and subsequent development of the acquired immunodeficiency syndrome (AIDS). LÄS MER